Evidence map›Paper›PMID 40636573›Full record

ArticleMethodsX2025

Growth and differentiation factors and their orthodontic implications: A scoping review.

Crystal Runa Soans, M S Ravi, Monisha P Chelery, Sujata Shirodkar, Prachi Pundir, Shradha S Parsekar

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in MethodsX, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Crystal Runa SoansDepartment of orthodontics and dentofacial orthopedics, Nitte (Deemed to be University), AB Shetty Memorial Institute of Dental Sciences, Mangalore, India.
M S RaviDepartment of orthodontics and dentofacial orthopedics, Nitte (Deemed to be University), AB Shetty Memorial Institute of Dental Sciences, Mangalore, India.
Monisha P CheleryDepartment of orthodontics and dentofacial orthopedics, Nitte (Deemed to be University), AB Shetty Memorial Institute of Dental Sciences, Mangalore, India.
Sujata ShirodkarCollaboration for Evidence Synthesis, Navelim, Goa, India.
Prachi PundirCollaboration for Evidence Synthesis, Navelim, Goa, India.
Shradha S ParsekarCollaboration for Evidence Synthesis, Navelim, Goa, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Growth and differentiation factors (GDFs) are a class of biological mediators that play an important role to stimulate and regulate the wound healing process. Some of the GDFs are known to play a role in orthodontics. Objectives: To map the evidence related to GDFs in orthodontics and to identify the role of GDFs in craniofacial morphogenesis, periodontal remodeling and orthodontic tooth movement. Methods: We have planned a scoping review to achieve the objectives. Search will be conducted in various databases to identify English language publications. Additionally, we will search the first ten pages of Google Scholar and the reference lists of included studies. This review will include all animal or human studies exploring preventive, interceptive and corrective treatments in orthodontics. Two reviewers will independently screen titles and abstracts and full-texts and extract the data of included studies. Disagreement will be resolved by discussion. The results will be presented in a descriptive format using diagrams and tables. Ethics and dissemination: The current study does not require ethical approval. Results of review findings will be disseminated through a peer-reviewed publication or conference presentation. Registration: The protocol is registered with the Open Science Framework.

Indexed as

A protocol of a Scoping reviewCraniofacial morphogenesisGDFsGrowth differentiation factorsOrthodonticsOrthodontic tooth movementPeriodontal remodelingScoping review

Identifiers

PMID40636573
PMCPMC12240163

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.