Evidence map›Paper›PMID 40636537›Full record

ArticleHealth science reports2025

Prevalence of HIV and HIV-Hepatitis B Co-Infection in Hepatocellular Carcinoma Patients in the Gambia, 2012-2019: A Prospective Cohort Study.

Sheikh Omar Bittaye, Abubacarr Kambi, Momodou A I Tekanyi, Saydiba Tamba, Lamin Bojang, Lamin Sanneh, Momodou Musa Sisawo, Abdoulie Jatta, Gibril Fatty, Adam Jeng and 3 more

Abstract read
PubMed Full text at PMC Publisher
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Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sheikh Omar BittayeDepartment of Internal Medicine Edward Francis Small Teaching Hospital Banjul The Gambia.ORCID https://orcid.org/0000-0001-8162-7363
Abubacarr KambiDepartment of Internal Medicine Edward Francis Small Teaching Hospital Banjul The Gambia.
Momodou A I TekanyiDepartment of Internal Medicine Edward Francis Small Teaching Hospital Banjul The Gambia.
Saydiba TambaDepartment of Internal Medicine Edward Francis Small Teaching Hospital Banjul The Gambia.
Lamin BojangDisease Control and Elimination MRC Unit The Gambia @ London School of Hygiene and Tropical Medicine Fajara The Gambia.
Lamin SannehDisease Control and Elimination MRC Unit The Gambia @ London School of Hygiene and Tropical Medicine Fajara The Gambia.
Momodou Musa SisawoDisease Control and Elimination MRC Unit The Gambia @ London School of Hygiene and Tropical Medicine Fajara The Gambia.
Abdoulie JattaDisease Control and Elimination MRC Unit The Gambia @ London School of Hygiene and Tropical Medicine Fajara The Gambia.
Gibril FattyDisease Control and Elimination MRC Unit The Gambia @ London School of Hygiene and Tropical Medicine Fajara The Gambia.
Adam JengDisease Control and Elimination MRC Unit The Gambia @ London School of Hygiene and Tropical Medicine Fajara The Gambia.
Momodou Salieu JallowSchool of Medicine and Allied Health Sciences University of The Gambia Banjul The Gambia.
Ousman LeighSchool of Medicine and Allied Health Sciences University of The Gambia Banjul The Gambia.
Ramou NjieDepartment of Internal Medicine Edward Francis Small Teaching Hospital Banjul The Gambia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: HIV-hepatitis B co-infection rapidly progresses to fibrosis, cirrhosis, and HCC and has a poor prognosis. The study therefore assesses the prevalence of HIV and HIV-hepatitis B co-infection in the Gambia. Methods: From June 2012 to September 2019, patients with confirmed diagnosis of HCC were enrolled. All patients medical history, ultrasound scan, fibroscan and laboratory details were collected. Results: The study recruited 476 HCC patients. The prevalence of HIV amongst the HCC patient was 21 (4.4%), and this was higher in males, 19 (4.9%), than in females, 2 (2.2%). The HCC patients with Hepatitis B only were 319 (67.2%). Those HCC patients with HIV-hepatitis B co-infection were 17 (3.6%). HCC patients with HIV-hepatitis B co-infection were much younger and more likely to be male as compared to HCC patients with Hepatitis B only or HCC patients with negative HIV-hepatitis B. There was no difference between the median survivals of the three HCC patient groups. Conclusions: The prevalence of HIV in HCC patients is higher than in the general population. HIV-hepatitis B disproportionately affects young men, but there was no difference in survival. This study therefore confirms the need to have an integrated HIV-hepatitis B services in Hepatology clinics or screening programs in the Gambia to early detect co-infections, especially in young men and start them on treatment to prevent chronic liver disease complications and improve prognosis.

Indexed as

Gambiahepatitis Bhepatocellular carcinomaHIV

Identifiers

PMID40636537
PMCPMC12239037

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.