Evidence map›Paper›PMID 40636529›Full record

ArticleHealth science reports2025

Normal Blood Pressure, High Normal Blood Pressure, and Risk of Incident Atrial Fibrillation: A Population-Based Cohort Study.

Cecilia Johansson, Lars Johansson, Marie Eriksson, Jonas Andersson, Marcus M Lind

Abstract read
In one paragraph

Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cecilia JohanssonDepartment of Public Health and Clinical Medicine, Skellefteå Research Unit Umeå University Skellefteå Sweden.ORCID https://orcid.org/0000-0001-9972-5893
Lars JohanssonDepartment of Public Health and Clinical Medicine, Skellefteå Research Unit Umeå University Skellefteå Sweden.
Marie ErikssonDepartment of Statistics, USBE Umeå University Umeå Sweden.
Jonas AnderssonDepartment of Public Health and Clinical Medicine, Skellefteå Research Unit Umeå University Skellefteå Sweden.
Marcus M LindDepartment of Public Health and Clinical Medicine, Skellefteå Research Unit Umeå University Skellefteå Sweden.ORCID https://orcid.org/0000-0003-4423-4135

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: This study aimed to investigate the association between normal BP, (blood pressure [BP] 120-129/80-84 mmHg), and high normal BP, (BP 130-139/85-89 mmHg), compared to optimal BP, and risk of atrial fibrillation (AF). Methods: A population-based cohort study was performed including inhabitants of Västerbotten County, Sweden, aged 30-60 years without AF at inclusion who participated in health examinations in 1988-2014. Approximately 40% of participants had ≥ 2 health examinations. The health examination included a questionnaire and measurement of BP, weight, height, and glucose. Cox regression with time-updated covariates was used to estimate the association between BP and AF risk. Restricted cubic spline analyses were performed. Results: The cohort included 109,697 persons with 162,982 observations and a mean follow-up of 13.6 years. Incident AF was diagnosed in 5260 participants. We found an increased risk of incident AF associated with normal BP (hazard ratio [HR] 1.13, 95% confidence interval [CI] 1.01-1.27) and high normal BP (HR 1.23, 95% CI 1.10-1.38) compared to optimal BP after multivariable adjustment. Systolic BP and diastolic BP in 10 mmHg increments were associated with risk of incident AF, with HRs of 1.11 (95% CI 1.10-1.13) and 1.13 (95% CI 1.09-1.16), respectively, in multivariable models. A restricted cubic spline analysis indicated that the AF risk increased gradually with increasing systolic and diastolic BP. Conclusion: Individuals with both normal BP and high normal BP have an increased risk of developing incident AF. The risk of AF increased gradually with increasing systolic and diastolic BP.

Indexed as

atrial fibrillationblood pressurecohort studyhypertensionrisk factor

Identifiers

PMID40636529
PMCPMC12239843

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.