Evidence map›Paper›PMID 40636460›Full record

ArticleiLIVER2025

Multiphase MRI radiomics model for predicting microvascular invasion in HCC: Development and clinical validation.

Yue Peng, Songxiong Wu, Bing Xiong, Fuqiang Chen, Nazar Zaki, Ruodai Wu, Wenjian Qin

Abstract read
In one paragraph

Article in iLIVER, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yue PengShenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Songxiong WuDepartment of Radiology, Shenzhen University General Hospital, Shenzhen University, Shenzhen 518000, China.
Bing XiongShenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Fuqiang ChenShenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Nazar ZakiDepartment of Computer Science and Software Engineering, College of Information Technology, United Arab Emirates University (UAEU), Al Ain 15551, United Arab Emirates.
Ruodai WuDepartment of Radiology, Shenzhen University General Hospital, Shenzhen University, Shenzhen 518000, China.
Wenjian QinUniversity of Chinese Academy of Sciences, Beijing 100049, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: Accurate preoperative prediction of microvascular invasion (MVI) in hepatocellular carcinoma (HCC) is crucial for treatment planning. This study aimed to develop and validate a multi-phase magnetic resonance imaging (MRI)-based radiomics model for predicting MVI in HCC patients. Methods: This retrospective study included 110 HCC patients (training: Results: The four-phase radiomics model with logistic regression classifier showed optimal performance in both the training (AUC = 0.896; 95% confidence interval, 0.792-0.963) and validation cohorts (AUC = 0.889, 95% confidence interval, 0.781-0.982), outperforming the single-phase (AUC = 0.789), two-phase (AUC = 0.815), and three-phase models (AUC = 0.848) in the validation cohort. In the validation cohort, the model achieved balanced performance with sensitivity, specificity, accuracy, and precision all reaching 0.857. Conclusions: The multi-phase MRI-based radiomics model significantly improves MVI prediction accuracy in HCC patients. This non-invasive approach could enhance preoperative assessment and treatment planning.

Indexed as

Hepatocellular carcinomaMicrovascular invasionMulti-phase MRI

Identifiers

PMID40636460
PMCPMC12209474

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.