Evidence map›Paper›PMID 40636453›Full record

ReviewJournal of immunology research2025

The Multifaceted Role of the IL-2 Cytokine Family in Melanoma: Mechanisms, Therapeutic Implications, and Immune Modulation.

Mona Daghaighei, Samaneh Dodge, Soheil Bolandi, Boutros Youssef, Niket Attarde, Moein Maddahi, Maryam Mostofi, Reza Morovatshoar, Mehrnaz Mostafavi, Dejbakht Majid and 6 more

Abstract readReview
In one paragraph

Review in Journal of immunology research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Mona DaghaigheiIslamic Azad University of Tehran, Medical Branch, Tehran, Iran.ORCID https://orcid.org/0009-0006-8352-8733
Samaneh DodgeSchool of Pharmacy, Shahid Beheshti University of Medical Science, Tehran, Iran.ORCID https://orcid.org/0009-0004-1900-624X
Soheil BolandiSchool of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.ORCID https://orcid.org/0000-0001-7907-8721
Boutros YoussefDepartment of Cardiovascular Diseases, Faculty of Medical Sciences, Lebanese University, Hadath, Lebanon.ORCID https://orcid.org/0000-0002-3846-2150
Niket AttardeDepartment of Medicine, Dr D Y Patil Medical College, Navi Mumbai, India.ORCID https://orcid.org/0009-0006-0005-318X
Moein MaddahiDepartment of Medicine, Yeditepe University of Medical Sciences, Istanbul, Türkiye.ORCID https://orcid.org/0009-0007-3176-5515
Maryam MostofiFaculty of Medicine, Ondokuz Mayis University, Samsun, Türkiye.ORCID https://orcid.org/0009-0000-4473-3482
Reza MorovatshoarMolecular Medicine Research Center, Hormozgan Health Institute, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.ORCID https://orcid.org/0000-0002-0247-7924
Mehrnaz MostafaviFaculty of Allied Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0001-7565-9908
Dejbakht MajidGerash Amir-al-Momenin Medical and Educational Center, Gerash University of Medical Sciences, Gerash, Iran.ORCID https://orcid.org/0000-0003-1266-3058
Mohammadamin JoulaniStudent Research Committee, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0003-4260-274X
Pegah TamimiSchool of Medicine, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0001-6606-4160
Malihe SharafiDepartment of Biology, Faculty of Basic Sciences, Azarbaijan Shahid Madani University, Tabriz, Iran.ORCID https://orcid.org/0009-0004-8962-9864
Qumars BehfarFaculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0001-5217-924X
Yasaman Ghodsi BoushehriSchool of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.ORCID https://orcid.org/0000-0003-2278-4849
Alireza AzaniDepartment of Medical Genetic, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0009-0005-0999-9871

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Interleukin-2MelanomaAnimalsDendritic CellsHumansImmunomodulationImmunotherapyTumor MicroenvironmentInterleukin-2cytokinesimmunotherapyinterleukininterleukin-2 familymelanoma

Identifiers

PMID40636453
PMCPMC12240660

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.