Evidence map›Paper›PMID 40636401›Full record

Articlenpj biomedical innovations2025

PodGPT: an audio-augmented large language model for research and education.

Shuyue Jia, Subhrangshu Bit, Edward Searls, Meagan V Lauber, Pengrui Fan, William M Wang, Lindsey A Claus, Varuna H Jasodanand, Divya Veerapaneni, Rhoda Au and 1 more

Abstract read
In one paragraph

Article in npj biomedical innovations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Shuyue Jia *Department of Electrical & Computer Engineering, Boston University, Boston, MA USA.
Subhrangshu Bit *Department of Computer Science, Boston University, Boston, MA USA.
Edward Searls *Department of Anatomy and Neurobiology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA USA.
Meagan V LauberDepartment of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA USA.
Pengrui FanDepartment of Computer Science, Boston University, Boston, MA USA.
William M WangDepartment of Computer Science, Boston University, Boston, MA USA.
Lindsey A ClausDepartment of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA USA.
Varuna H JasodanandDepartment of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA USA.
Divya VeerapaneniDepartment of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA USA.
Rhoda AuDepartment of Anatomy and Neurobiology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA USA.
Vijaya B KolachalamaDepartment of Computer Science, Boston University, Boston, MA USA.

Funding

TBDU19AG068753 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Thor Stein · 2020 to 2026
$42.4M
Utilizing Technology and AI Approaches to Facilitate Independence andResilience in Older AdultsP30AG073104 · NIA · JOHNS HOPKINS UNIVERSITY · PI Alexis Battle · 2021 to 2026
$31.2M
Technology Identification and Training CoreP30AG073105 · NIA · UNIVERSITY OF PENNSYLVANIA · PI DEMIRIS, GEORGE, KARLAWISH, JASON H · 2021 to 2025
$21.2M
Digital Cognitive Assessment of Preclinical Alzheimer's Disease and Related DementiasR01AG083735 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Rhoda Au, Vijaya B. Kolachalama · 2024 to 2026
$2.4M
Mechanisms of drug-coated balloon therapyR01HL159620 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI KOLACHALAMA, VIJAYA B. · 2021 to 2024
$2.1M
Digital Neurodegenerative Pathology After Repetitive Head ImpactsR01NS142076 · NINDS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Jonathan D Cherry, Vijaya B. Kolachalama · 2025 to 2026
$1.7M
Cognitive heterogeneity in those with high Alzheimer's Disease RiskR01AG062109 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Rhoda Au, Vijaya B. Kolachalama · 2025 to 2026
$1.6M
NHLBI NIH HHS R01 HL159620NIA NIH HHS P30 AG073104NIA NIH HHS P30 AG073105NIA NIH HHS R01 AG062109NIA NIH HHS R01 AG083735NIA NIH HHS U19 AG068753NINDS NIH HHS R01 NS142076
6 · The paper itself

Abstract

The proliferation of scientific podcasts has generated an extensive repository of educational content, rich in specialized terminology, diverse topics, and expert dialogues. Here, we introduce a computational framework designed to enhance large language models by leveraging this informational content from publicly accessible audio podcasts across science, technology, engineering, mathematics, and medicine (STEMM). This dataset, comprising over 3700 hours of audio content, was transcribed to generate over 42 million text tokens. Our model, PodGPT, integrates this wealth of complex dialogue found in audio podcasts to improve understanding of natural language nuances, cultural contexts, as well as scientific and medical knowledge. PodGPT also employs retrieval augmented generation (RAG) on a vector database, providing real-time access to emerging scientific literature. Evaluated on multiple benchmarks, PodGPT demonstrated an average improvement of 1.82 percentage points over standard open-source benchmarks and 2.43 percentage points when augmented with evidence from the RAG pipeline. Moreover, it showcased an average improvement of 1.18 percentage points in its zero-shot multilingual transfer ability, effectively generalizing to different linguistic contexts. By harnessing the untapped potential of podcast content, PodGPT advances natural language processing and conversational AI, offering enhanced capabilities for STEMM research and education.

Indexed as

Computational biology and bioinformaticsMedical research

Identifiers

PMID40636401
PMCPMC12234354

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.