ArticleFrontiers in medicine2025
Effect of multiple intravitreal injections of conbercept on the cornea in patients with branch retinal vein occlusion-induced macular edema.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
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4 authors.
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Abstract
Background: To investigate the effect of multiple intravitreal injections of conbercept on the cornea in patients with branch retinal vein occlusion (BRVO)-induced macular edema. Methods: The retrospective study analyzed the clinical data of 40 patients (40 eyes) with BRVO-induced macular edema between March 2020 and March 2023. All patients received intravitreal injections of conbercept according to the "3 + PRN" regimen and were followed for at least 6 months. Corneal analysis was performed using a corneal endothelial microscope and a Pentacam corneal topographic map. The best-corrected vision acuity (BCVA), central retinal thickness, central corneal thickness, corneal endothelial cell density, hexagonal cell percentage, and coefficient of variation before and at 1, 3, and 6 months after the injection were compared. Results: The study included 40 patients (22 males and 18 females) with an average age of 50.80 ± 7.35 years (range, 38-67 years). The corneal endothelial cell densities, central corneal thicknesses, hexagonal cell percentages, and coefficients of variation before and at 1, 3, and 6 months after the injection were not significantly different ( Conclusion: Multiple intravitreal injections of conbercept can improve the BCVA and reduce macular edema in patients with BRVO and have no significant effect on the cornea.
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