ArticleFrontiers in medicine2025
Safety and efficacy of ciprofol for general anesthesia induction in elderly patients undergoing lumbar surgery.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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6 authors.
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Abstract
Objective: This study aimed to evaluate the safety and efficacy of ciprofol for anesthesia induction in elderly patients undergoing lumbar surgery. Methods: Sixty patients aged 65-80 years scheduled for elective lumbar surgery under general anesthesia were randomly divided into two groups ( Results: Both groups showed comparable time to achieve target anesthetic depth and similar trends in hemodynamic changes. However, the ciprofol group demonstrated significantly lower incidence of hypotension compared to the propofol group (20% vs. 63%, Conclusion: Ciprofol demonstrates comparable safety and efficacy to propofol for anesthesia induction in elderly patients undergoing lumbar surgery, with superior hemodynamic stability, supporting its clinical application in geriatric lumbar surgery. Clinical trial registration: The trial was registered, before patient enrollment, in the Chinese Clinical Trial Registry (www.chictr.org.cn) (Clinical trial number: ChiCTR2300069858, https://www.chictr.org.cn/showproj.html?proj=192839, principal investigator's name: Gang Yao, date of registration: 28/03/2023).
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