Evidence map›Paper›PMID 40636344›Full record

ReviewiLIVER2022

Transarterial chemoembolization in combination with programmed death-1/programmed cell death-ligand 1 immunotherapy for hepatocellular carcinoma: A mini review.

Jingxin Yan, Manjun Deng, Shunyu Kong, Ting Li, Zhenwu Lei, Lushun Zhang, Yutong Zhuang, Xin He, Huanwei Wang, Haining Fan and 1 more

Erratum issuedAbstract readReview
In one paragraph

Review in iLIVER, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. PD1Cancer immunology, immunotherapy : CII · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Jingxin YanDepartment of Interventional Therapies, Affiliated Hospital of Qinghai University, Xining, China.
Manjun DengDepartment of Hepatopancreatobiliary Surgery, Affiliated Hospital of Qinghai University, Xining, China.
Shunyu KongDepartment of Interventional Therapies, Affiliated Hospital of Qinghai University, Xining, China.
Ting LiDepartment of Orthopedics, Sichuan Provincial People's Hospital, Chengdu, China.
Zhenwu LeiDepartment of Interventional Therapies, Affiliated Hospital of Qinghai University, Xining, China.
Lushun ZhangDepartment of Pathology and Pathophysiology, Chengdu Medical College, Chengdu, China.
Yutong ZhuangDepartment of Neurosurgery, The Second School of Clinical Medicine, Southern Medical University, Guangzhou 510515, Guangdong, China.
Xin HeDepartment of Postgraduate, Qinghai University, Xining, China.
Huanwei WangDepartment of Postgraduate, Qinghai University, Xining, China.
Haining FanDepartment of Hepatopancreatobiliary Surgery, Affiliated Hospital of Qinghai University, Xining, China.
Yingxing GuoDepartment of Interventional Therapies, Affiliated Hospital of Qinghai University, Xining, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide. With the development of systemic therapies, several studies are currently underway, especially those related to the use of programmed death-1/programmed cell death-ligand 1 (PD-1/PD-L1) immunotherapy. Moreover, studies on transarterial chemoembolization (TACE) and PD-1/PD-L1 immunotherapy have demonstrated some interesting outcomes. This article reviewed the current clinical evidence on the combination of TACE and PD-1/PD-L1 immunotherapy. Overall, our review summarized that a favorable survival time could be achieved using this combination in most patients. However, complications such as hyperprogression should be taken seriously, and the underlying mechanisms need to be explored.

Indexed as

Clinical evidenceHepatocellular carcinomaProgrammed cell death-ligand 1Programmed death 1Transarterial chemoembolization

Identifiers

PMID40636344
PMCPMC12212740

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.