Evidence map›Paper›PMID 40636331›Full record

ArticleJournal of biomedical optics2024

Critical analysis of the relationship between arterial saturation and the ratio-of-ratios used in pulse oximetry.

Giles Blaney, Angelo Sassaroli, Sergio Fantini

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Real-Time SpOSensors (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Giles BlaneyTufts University, Department of Biomedical Engineering, Medford, Massachusetts, United States.ORCID 0000-0003-3419-4547
Angelo SassaroliTufts University, Department of Biomedical Engineering, Medford, Massachusetts, United States.ORCID 0000-0003-4233-7165
Sergio FantiniTufts University, Department of Biomedical Engineering, Medford, Massachusetts, United States.ORCID 0000-0001-5116-525X

Funding

Dual-slope method for enhanced depth sensitivity in frequency-domain near-infrared spectroscopyR01EB029414 · NIBIB · TUFTS UNIVERSITY MEDFORD · PI SERGIO FANTINI · 2021 to 2026
$2.5M
NIBIB NIH HHS R01 EB029414
6 · The paper itself

Abstract

Significance: Pulse oximetry is a well-established technique for the assessment of arterial oxygen Saturation ( Aim: We aim to derive and discuss the quantitative relationship between Approach: The source of the pulsatile optical signal is the systolic and diastolic pulsation of the arterial compartment within the probed tissue. From a diffuse optics point of view, this is associated with an absorption change in the region that arterial blood expands into and a mean partial optical path length through that expanded arterial volume. This observation is the basis for a modified Beer-Lambert law analysis of the relationship between Results: The equation that relates Conclusion: The analysis reported here clarifies the source of the calibration equations used in pulse oximetry and provides guidance to assess the impact of various key optical parameters on the accuracy of pulse oximetry.

Indexed as

ArteriesOximetryOxygenOxygen SaturationHemoglobinsHumansOxyhemoglobinsHemoglobinsOxygenOxyhemoglobinsblood oxygen saturationnear-infrared spectroscopyoptical pulse oximetry

Identifiers

PMID40636331
PMCPMC12238718

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.