Evidence map›Paper›PMID 40636211›Full record

ArticleBioinformation2025

Cytotoxic and apoptotic effects of novel phytochemical extracts on oral squamous cell carcinoma cells.

Sweta Singh, Nishita Anthwal, Ankur Joshi, Rajni Saini, Vipin Arora, Abhishek Moharana

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sweta SinghDepartment of Oral Pathology and Microbiology, Subharti Dental College, Meerut - 250002, India.
Nishita AnthwalDepartment of Oral Pathology and Microbiology, Uttaranchal Dental and Medical Research Institute, Haridwar, Majri -Dehradun, Uttarakhand - 248140, India.
Ankur JoshiDepartment of Dentistry, Government Medical College, Haridwar, Uttarakhand - 249401, India.
Rajni SainiDepartment of Oral Pathology and microbiology, Himachal Institute of Dental Sciences, Paonta Sahib, Rampurghat, Sirmaur - 173025, Himachal Pradesh, India.
Vipin AroraDepartment of Restorative Dental Sciences, Taif University, Kingdom of 21944-Saudi Arabia.
Abhishek MoharanaDepartment of Oral Medicine and Radiology, Kalinga Institute of Dental Sciences, Bhubaneswar, KIIT (Deemed to be University), Patia, Bhubaneswar, Odisha, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The oral squamous cell carcinoma has inadequate treatment methods. Therefore, it is of interest to investigate the effect of new phytochemical extracts on both cell death and programmed cell death of OSCC cells. The phytochemical extracts tested at different concentrations produced a decrease in cell survival which dropped from 85% to 40% (p < 0.05) and led to increased apoptotic death from 15% to 60%. Caspase-3 activation tests showed both apoptotic changes and morphological developments at the cellular level for further consideration through

Indexed as

anticancer therapyapoptosiscaspase-3cytotoxicityOral squamous cell carcinoma (OSCC)phytochemicals

Identifiers

PMID40636211
PMCPMC12236559

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.