Evidence map›Paper›PMID 40636205›Full record

ArticleBioinformation2025

Management of oral sub-mucous fibrosis using platelet-rich plasma and triamcinolone with hyaluronidase.

Ajay Kumar, Adit Srivastava, Neha Sah, Amlendu Shekhar, Sivani Darjee, Saumya Shukla, Vinayalekshmy In Nair, Mahesh Khairnar, Ashutosh Kumar Rai

Abstract read
In one paragraph

Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ajay KumarDepartment of Oral medicine and radiology, Institute of medical sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Adit SrivastavaDepartment of Oral medicine and radiology, Institute of medical sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Neha SahDepartment of Dentistry, Maa Vindhyavasini Autonomous State Medical College, Mirzapur, Uttar Pradesh, India.
Amlendu ShekharDepartment of Oral medicine and radiology, Institute of medical sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Sivani DarjeeDepartment of Oral medicine and radiology, Institute of medical sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Saumya ShuklaDepartment of Oral medicine and radiology, Institute of medical sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Vinayalekshmy In NairDepartment of Oral medicine and radiology, Institute of medical sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Mahesh KhairnarDepartment of Oral medicine and radiology, Institute of medical sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Ashutosh Kumar RaiDepartment of Oral medicine and radiology, Institute of medical sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral Submucous Fibrosis (OSMF) is a chronic, progressive and potentially malignant disorder of the oral mucosa, primarily associated with betel quid and areca nut chewing. Therefore, it is of interest to compare the efficacy of intralesional Platelet-Rich Plasma (PRP) versus triamcinolone acetonide with hyaluronidase in the treatment of oral submucous fibrosis. This is a randomized clinical trial was conducted at the unit of oral medicine and radiology, Faculty of Dental Sciences, IMS, Banaras Hindu University (BHU), Varanasi. Patients diagnosed with grade II and III oral submucous fibrosis participated in this study. Results show that intralesional PRP was more effective than the combination of triamcinolone acetonide and hyaluronidase in the management of oral submucous fibrosis.

Indexed as

hyaluronidaseOral submucous fibrosis (OSMF)platelet-rich plasma (PRP)randomized clinical trialtriamcinolone acetonide

Identifiers

PMID40636205
PMCPMC12236549

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.