Bone regeneration using PRF, PRP and β-TCP in bone defects.

Vipin Arora, Ankur Joshi, Nishita Anthwal, Sameer Gupta, Ashtha Arya, Mahima Paul

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In one paragraph

Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Vipin AroraDepartment of Restorative Dental Sciences, Taif University, Kingdom of Saudi Arabia - 21944.

Ankur JoshiDepartment of Dentistry, Government Medical College, Haridwar - 249401, Uttarakhand, India.

Nishita AnthwalDepartment of Oral Pathology and Microbiology, UDMRI, Dehradun, Uttarakhand - 248140, India.

Sameer GuptaDepartment of Oral and Maxillofacial Surgery, Inderprastha Dental College and Hospital, Sahibabad, Ghaziabad, Uttar Pradesh, - 201010, India.

Ashtha AryaDepartment of Conservative Dentistry and Endodontics, SGT Dental College, Hospital and Research Institute, SGT University, Gurugram, Haryana - 122505, India.

Mahima PaulDepartment of Oral Medicine and Radiology, ⁠Kalinga Institute of Dental Sciences, KIIT Deemed To Be University, Patia, Bhubaneswar, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone regeneration using platelet-rich fibrin (PRF), platelet-rich plasma (PRP) and beta-tricalcium phosphate (β-TCP) in bone defects is of interest. PRF achieved the maximum bone fill (85%) during the 12 weeks assessment period while PRP and β-TCP reached 75% and 65% bone fill, respectively. Trabecular bone density proved superior in defects treated with PRF according to the histological findings (p < 0.05). The prolonged availability of growth factors from PRF resulted in better bone tissue formation. The biomaterial PRF demonstrates strong potential to become an effective solution for efficient bone healing in clinical medicine.

Indexed as

beta-tricalcium phosphate (β-TCP)bone defectsBone regenerationosteogenesisplatelet-rich fibrin (PRF)platelet-rich plasma (PRP)

Identifiers

PMID40636164

DOI10.6026/973206300210793

PMCPMC12236558

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