ArticleMaterials today. Bio2025
Resveratrol-loaded engineered microcapsules with dual antimicrobial and ROS-scavenging for programmed wound healing.
Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Engineering alginate hydrogels loaded with resveratrol as a dual platform for cancer therapy and wound regeneration.Discover nano · 2026Review
- Attenuated Bacteria-Based Tumor Therapy: Clinical Application Risks, Marketing Approval Restrictions, and Coping Strategies.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Development and characterization of composite hydrogels loaded with hawthorn flavonoid microcapsules: Application in cold pork.Food chemistry: X · 2025Article
- Investigating the molecular mechanisms of resveratrol in treating diabetic foot ulcers: a comprehensive analysis of network pharmacology and experiment validation.Frontiers in molecular biosciences · 2025Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hydrogel microparticles have been proved effective for the skin wound repair. Attempts in this area focus on how to enrich the structures and encapsulate bioactive substances to achieve the spatially controllable release for accelerated wound healing. Here, we propose a novel core-shell microcapsule delivery system with the spatial encapsulation and release of resveratrol (RSV) and chitosan (CS) to treat infected wounds. Such microcapsules (ALG-CS) were generated through microfluidic electrospray technology, with the inner core encapsulating RSV and outer layer covered with the imine bond-crosslinked CS hydrogel. The designed CS hydrogel coating can improve the stability of microcapsules and further prevent the premature leakage of RSV. The gradually degraded CS hydrogel layer in acidic environment accompanied with the subsequent release RSV contributed to the enhanced antibacterial properties of the microcapsules. In addition, the released RSV exhibited outstanding antioxidant capacities to protect cells from oxidative stress
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