ArticleMaterials today. Bio2025
Dissolvable microneedle-assisted transdermal administration of diacerein nanoparticles achieved satisfactory therapeutic effects in tendon-bone insertion repair by reducing oxidative stress and inflammation.
Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Neonatal muscle-derived extracellular vesicles containing miR-542-3p rejuvenate aged skeletal muscle via a functional microneedle patch.Bioactive materials · 2026Article
- Strontium‑based metal‑organic framework/alendronate‑silk fibroin hydrogels promote tendon‑bone interface healing.Molecular medicine reports · 2026Article
- On-demand mild photothermal cascade platform reprogramming mitochondrial immunity for tendon rejuvenation.Bioactive materials · 2026Article
- ROS scavenging nanoengineered bioactive glass interfaces reprogram macrophage immunity for tendon-bone regeneration.Regenerative biomaterials · 2026Article
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Authors and funding
11 authors.
Funding
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Abstract
Tendon-bone insertion injuries are frequently encountered in sports medicine clinics, with the healing process posing a significant challenge within this field. When it comes to non-surgical interventions for such injuries, the use of local drug injections may carry the risk of damaging peripheral nerves and blood vessels. In this study, a simple dissolvable microneedle (DMN) patch loaded with diacerein (Dia) nanoparticles (DMN/PLGA@Dia) is established to achieve a constant delivery of Dia for enhancing tendon-bone healing.
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