Evidence map›Paper›PMID 40635846›Full record

ArticleAJP reports2025

A Comparison of Severe Maternal Morbidity After Pre- and Periviable Premature Prelabor Rupture of Membranes in Multiple Gestations: Expectant Management versus Pregnancy Termination.

Courtney T Connolly, Siwei Xie, Ethan Gough, Marika A Toscano

Abstract read
In one paragraph

Article in AJP reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Courtney T ConnollyDepartment of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Siwei XieJohns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Ethan GoughJohns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Marika A ToscanoDepartment of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Funding

Johns Hopkins Women's Reproductive Health Research Career Development ProgramK12HD103036 · NICHD · JOHNS HOPKINS UNIVERSITY · PI SATIN, ANDREW J. · 2020 to 2024
$1.5M
NICHD NIH HHS K12 HD103036
6 · The paper itself

Abstract

Objective: To compare severe maternal morbidity (SMM) and mortality after pre- or periviable prelabor rupture of membranes (pPPROM) in multiple gestation pregnancies among individuals choosing expectant management (EM) or termination of pregnancy (TOP). Study Design: A retrospective cohort study of multiple gestations with pPPROM between 14 Results: Forty-five twin and 1 triplet gestations were included ( Conclusion: One in four individuals with multiple gestations undergoing EM of pPPROM experienced at least one adverse maternal outcome by CDC criteria. There were no significant differences identified between EM and TOP, likely due to the study's limited size. Key Points: More than 70% of multiples with pPPROM electing EM experienced an adverse maternal outcome.There was no difference in maternal morbidity detected between EM and termination.One in four multiples with pPPROM electing EM had a severe adverse maternal outcome.Given disparities in access to termination, understanding maternal risks of pPPROM is critical.

Indexed as

adverse outcomesmaternal complicationsmaternal morbiditymultiple gestationpreterm prelabor rupture of membranes

Identifiers

PMID40635846
PMCPMC12240663

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.