ArticleFrontiers in neurology2025
Structural and functional disconnections in non-acute post-stroke patients.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Structural-functional connectivity coupling in motor-brain networks following acute ischemic stroke.Journal of neuroengineering and rehabilitation · 2026Article
- Comparative efficacy and mechanistic insights of non-invasive neuromodulation and motor rehabilitation on functional reorganization of the supplementary motor area in subacute stroke: a narrative review.Frontiers in physiology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Structural alterations and functional reorganizations related to motor dysfunction after stroke remain unclear. This study aims to investigate alterations in structural connectivity (SC) and functional connectivity (FC) in non-acute post-stroke patients, and their associations with motor performance. Methods: Thirty-six non-acute post-stroke patients and thirty-eight well-matched healthy controls (HCs) were included. SC and FC differences between groups were analyzed using diffusion tensor imaging and resting-state fMRI, respectively. Correlations between SC and FC in regions with significant intergroup differences, along with their correlations with motor performance, were assessed. Results: Compared with HCs, significant decreases in both SC and FC were observed in stroke patients among the right precentral gyrus, right superior frontal gyrus, right supplementary motor area, right paracentral lobule, right middle cingulate gyrus, right superior marginal gyrus, right middle temporal gyrus, and left inferior temporal gyrus. A negative correlation of SC-FC was found between the right middle cingulate gyrus and right paracentral lobule in stroke group, while a positive correlation was found between the right superior marginal gyrus and right middle temporal gyrus. Moreover, the FC between the right superior marginal gyrus and right middle temporal gyrus showed negative correlations with the Fugl-Meyer assessment of the Upper/Lower Extremity scores. Discussion: This study identified disconnections in both SC and FC in sensorimotor-related and high-order brain regions, which may enhance understanding of the structure-function interactions underlying motor deficits in post-stroke patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.