Evidence map›Paper›PMID 40635692›Full record

SynthesisFrontiers in bioengineering and biotechnology2025

Effectiveness of bone expansion, compacting and densification in narrow alveolar crests: a systematic review and a meta-analysis.

Nansi López-Valverde, Antonio López-Valverde, José Antonio Blanco

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nansi López-ValverdeDepartment of Surgery, Faculty of Medicine, University of Salamanca, Salamanca, Spain.
Antonio López-ValverdeDepartment of Surgery, Faculty of Medicine, University of Salamanca, Salamanca, Spain.
José Antonio BlancoDepartment of Surgery, Faculty of Medicine, University of Salamanca, Salamanca, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The treatment of edentulism with dental implants is a common and reliable procedure with high medium- and long-term survival rates. Primary stability in the bone is vitally important to prevent micro-movements at the beginning of healing. However, the main drawback of dental implantology is bone deficiency. To alleviate this situation, clinicians' resort to surgical techniques that increase bone volume and allow the devices to be placed. Bone expansion, compaction, and densification are used to compact the bone trabeculae, densifying the bone and improving the primary stability and osseointegration of implants. The aim of the study was to evaluate the role of these surgical techniques in deficient alveolar ridges in order to prepare them to receive durable dental implants. Methods: Searches were made of the PubMed/Medline, Embase, Cochrane Central, Dentistry and Oral Sciences Source and Web of Science (WOS) databases and GreyNet International, to identify RCTs, prospective studies, retrospective studies and case series published in English in the last 15 years, which evaluated the efficacy of bone expansion, bone compaction and densification in narrow alveolar ridges and their impact on bone density (BD), alveolar ridge expansion (CE) and implant stability quotient (ISQ). Methodological quality was evaluated using the Joanna Briggs Institute for RCTs (JBI MAStARI) tool and risk of bias using the Cochrane Risk of Bias Tool (RoB2), and meta-analyses were performed using Review Manager 5.4.1 software to calculate effect size and integrate the results of the included studies. Results: Ten of the 2,464 studies examined met the inclusion criteria. The meta-analysis of the parameters analyzed was favorable for the experimental group, indicating that bone expansion, compaction and densification techniques significantly increase DB (-0.71, 95% CI (Confidence Interval) [-1.15 to -0.27], p = 0.002), EC (-1.12, 95% CI [-2.21 to -0.03], p = 0.04) and ISQ (-8.88, 95% CI [-13.85 to -3.91], p = 0.0005), with a high publication bias for CE and ISQ. Conclusion: The techniques of bone expansion, compaction and densification demonstrated their effectiveness in narrow alveolar ridges, although studies are needed to validate the results found. Systematic Review Registration: Identifier CRD42025646738.

Indexed as

bone compactionbone densificationcrestal expansionnarrow alveolar ridgeosteotomesthreaded expanders

Identifiers

PMID40635692
PMCPMC12238099

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.