Evidence map›Paper›PMID 40635471›Full record

ArticlePsychophysiology2025

Loneliness Is Associated With Decreased Support and Increased Strain Given in Social Relationships.

Emily M Kent, Anita Restrepo, Kelly E Faig, Sabina Raja, Stephanie J Dimitroff, Karen E Smith, Greg J Norman

Abstract read
In one paragraph

Article in Psychophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Quality over Quantity: The Association Between Daily Social Interactions and Loneliness.International journal of environmental research and public health · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Emily M KentDepartment of Psychology, University of Chicago, Chicago, Illinois, USA.ORCID 0000-0002-2456-1481
Anita RestrepoDepartment of Psychology, University of Chicago, Chicago, Illinois, USA.ORCID 0000-0003-1185-8873
Kelly E FaigDepartment of Psychology, Hamilton College, Clinton, New York, USA.ORCID 0000-0002-7394-071X
Sabina RajaDepartment of Psychology, University of Chicago, Chicago, Illinois, USA.ORCID 0000-0002-4427-4682
Stephanie J DimitroffDepartment of Psychology, University of Montana, Missoula, Montana, USA.ORCID 0000-0001-9293-9792
Karen E SmithDepartment of Psychology, Rutgers University - Newark, Newark, New Jersey, USA.ORCID 0000-0002-6689-7346
Greg J NormanDepartment of Psychology, University of Chicago, Chicago, Illinois, USA.ORCID 0000-0003-2899-3238

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
Maternal Morbidity and Mortality: Risk Factors, Early Detection and Personalized InterventionUL1TR001409 · NCATS · GEORGETOWN UNIVERSITY · PI GONDRE-LEWIS, MARJORIE C, MELLMAN, THOMAS A · 2015 to 2024
$37.8M
NCATS NIH HHS UL1 TR001409NCATS NIH HHS UL1 TR001881NIA NIH HHS U19-AG051426
6 · The paper itself

Abstract

Prolonged loneliness can be detrimental to both mental and physical health. However, variability in how individuals respond to loneliness can shape health outcomes. Here, we explored whether loneliness is related to perceptions of support and strain given in family and friend relationships. Specifically, we assessed whether resting high-frequency heart rate variability (HF-HRV), a measure of parasympathetic nervous system activity that has been linked to emotion regulation and flexible adaptation, moderates self-evaluation of support and strain given. Participants from the Midlife Development in the US (MIDUS) dataset who had measures of loneliness, perceived support given, and perceived strain given in relationships, and resting HF-HRV were included in the current study. Loneliness was associated with decreased support and increased strain given in both family and friend relationships. Resting HF-HRV showed a trend-level moderation of the association between loneliness and perceived strain given to family, with the relationship being stronger for individuals with lower resting HF-HRV. No moderation was observed for strain given to friends. These results indicate that loneliness is linked to more negative self-evaluations of social support and strain, and that resting HF-HRV may partly buffer these effects in family relationships.

Indexed as

Family RelationsFriendsHeart RateInterpersonal RelationsLonelinessParasympathetic Nervous SystemSocial SupportStress, PsychologicalAdultAgedFemaleHumansMaleMiddle Agedlonelinessparasympatheticstrainsupport

Identifiers

PMID40635471
PMCPMC12242097

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.