Evidence map›Paper›PMID 40635344›Full record

ArticleCroatian medical journal2025

The application of paravertebral block for open cholecystectomy in a high-risk patient with an implantable cardioverter-defibrillator: a case report.

Miroslav Župčić, Katarina Tomulić Brusich, Tin Nadarević, Sandra Graf Župčić, Viktor Duzel, Gzim Redžepi

Abstract readCase Reports
In one paragraph

Article in Croatian medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Miroslav ŽupčićMiroslav Župčić, Department of Anesthesiology, Intensive Care and Pain Medicine, Clinical Hospital Center Rijeka, Krešimirova st. 42, 51000 Rijeka, Croatia, miroslav.zupcic@uniri.hr.
Katarina Tomulić Brusich
Tin Nadarević
Sandra Graf Župčić
Viktor Duzel
Gzim Redžepi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a case of a 57-year-old male patient (American Society of Anesthesiologists status IV) undergoing open cholecystectomy under unilateral thoracic paravertebral block (TPVB) and sedation. The patient had severe heart failure, a reduced ejection fraction of approximately 16%, and an implanted subcutaneous implantable cardioverter-defibrillator. Using ultrasound, we identified the thoracic (Th) paravertebral spaces on the right side at four levels (from Th6 to Th9) and administered 3.5 mL of 0.5% levobupivacaine per level, for a total of 14 mL. Twenty minutes after TPVB application, we confirmed sensory blockade from the Th5 to Th10 dermatomes. Ten minutes into surgery, during liver capsule retraction, the patient experienced some pain (5/10 on the visual analogue scale, VAS). The pain was successfully treated with rescue analgesia of 10 µg of intravenous (IV) sufentanil and a sedation dose of 50 mg IV propofol. The surgery lasted 45 minutes and was completed uneventfully. For continued intraoperative sedation, we used 10 mg/h remimazolam, maintaining hemodynamic stability. Nine hours after surgery, the patient reported a VAS pain score of 5 and received 75 mg of IV diclofenac sodium, with no further analgesia required. The patient was discharged on postoperative day six. In conclusion, the application of TPVB combined with remimazolam sedation could present a feasible anesthetic and analgesic technique for open cholecystectomy in high-risk cardiac patients.

Indexed as

CholecystectomyDefibrillators, ImplantableHeart FailureNerve BlockAnesthetics, LocalBupivacaineHumansLevobupivacaineMaleMiddle AgedPostoperative PainAnesthetics, LocalBupivacaineLevobupivacaine

Identifiers

PMID40635344
PMCPMC12246965

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.