Trial reportCroatian medical journal2025
Regional anesthesia without opioid administration in mastectomy surgeries followed by breast reconstruction with implants: a randomized controlled study.
Trial report in Croatian medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- The Underrated Burden of Post-Mastectomy Pain: A Call for Long-Term Surveillance and Holistic Care.Asian Pacific journal of cancer prevention : APJCP · 2025Article
- Refining anesthesia practice - regional techniques, risk stratification, and evidence-based analgesia.Croatian medical journal · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo compare regional anesthesia without opioid administration following subcutaneous mastectomy and breast reconstruction with implants in the pre-pectoral plane with general anesthesia in terms of pain relief, opioid consumption, and hospital stay duration.
methodsThis randomized controlled study enrolled patients who underwent mastectomy with reconstruction of the breast either with permanent implants or tissue expander placement in the pre-pectoral plane. A total of 40 patients met the inclusion criteria. The regional anesthesia group (n=20) received a pectoralis muscle block (PECS I), thoracic paravertebral block (TPVB), and serratus anterior muscle plane block (SAP) following a uniform protocol, and the control group (n=20) underwent general anesthesia. Pain was assessed by using the numeric rating scale (NRS) from 30 minutes after surgery up to ten days postoperatively.
resultsNRS pain scores were significantly higher in the regional anesthesia group, independent of the patients' physical daily activity level, even up to 10 days after surgery. Opioid consumption and length of hospital stay did not differ significantly.
conclusionRegional anesthesia using a combination of a TBVP, PECS I, and SAP has a long-lasting and satisfactory analgesic effect without the introduction of opioids. In the future, a novel gold standard protocol should be established that can be offered to every patient undergoing breast surgery.
Indexed as
Identifiers
40635342PMC12246971What OpenQuestion holds
Registered trials
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