Evidence map›Paper›PMID 40635287›Full record

ReviewJournal of environmental science and health. Part C, Toxicology and carcinogenesis2025

Potential anticancer effects and toxicity of flavones luteolin and apigenin

Xilin Li, Yuxi Li, Si Chen, Lei Guo, Nan Mei

Abstract readReview
In one paragraph

Review in Journal of environmental science and health. Part C, Toxicology and carcinogenesis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xilin LiDivision of Genetic and Molecular Toxicology, National Center for Toxicological Research, Jefferson, AR, USA.ORCID 0000-0003-0465-6958
Yuxi LiDivision of Biochemical Toxicology, National Center for Toxicological Research, Jefferson, AR, USA.
Si ChenDivision of Biochemical Toxicology, National Center for Toxicological Research, Jefferson, AR, USA.
Lei GuoDivision of Biochemical Toxicology, National Center for Toxicological Research, Jefferson, AR, USA.
Nan MeiDivision of Genetic and Molecular Toxicology, National Center for Toxicological Research, Jefferson, AR, USA.

Funding

Intramural FDA HHS FD999999
6 · The paper itself

Abstract

Luteolin and apigenin, which are abundantly present in various vegetables, fruits, and herbs, have emerged as noteworthy candidates for therapeutic applications. Traditionally recognized for their anti-inflammatory and antioxidant activities, both luteolin and apigenin have recently demonstrated the ability to inhibit cancer cell growth across multiple cancer types

Indexed as

Antineoplastic AgentsApigeninLuteolinNeoplasmsAnimalsHumansAntineoplastic AgentsApigeninLuteolinanimal modelanticancerapigeninFlavonesluteolin

Identifiers

PMID40635287
PMCPMC12376139

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.