Evidence map›Paper›PMID 40635251›Full record

ArticleMedical science monitor : international medical journal of experimental and clinical research2025

Incremental Prognostic Value of Right and Left Atrial Volume Indices for Predicting Cardiovascular Outcomes in Atrial Fibrillation: A Cohort Study.

Ferit Böyük, Wenli Gu, Ching-Yan Zhu, Jingnan Zhang, Yan Chen, Meizhen Wu, Qingwen Ren, Kai-Hang Yiu

Abstract read
In one paragraph

Article in Medical science monitor : international medical journal of experimental and clinical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ferit BöyükDepartment of Cardiology, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, İstanbul, Turkey.ORCID 0000-0003-2313-1495
Wenli GuDivision of Cardiology, Department of Medicine, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong, China.
Ching-Yan ZhuDivision of Cardiology, Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China.
Jingnan ZhangDivision of Cardiology, Department of Medicine, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong, China.
Yan ChenDepartment of Ultrasound, Shenzhen Hospital of Southern Medical University, Shenzhen, Guangdong, China.
Meizhen WuDivision of Cardiology, Department of Medicine, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong, China.
Qingwen RenDivision of Cardiology, Department of Medicine, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong, China.
Kai-Hang YiuDivision of Cardiology, Department of Medicine, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND Atrial fibrillation (AF) is a common arrhythmia associated with high morbidity and mortality. While the left atrial volume index (LAVI) is a known prognostic marker, the right atrial volume index (RAVI) in this setting remains less well defined. This study aimed to investigate the incremental prognostic value of the RAVI alongside the LAVI in predicting adverse cardiovascular outcomes in patients with AF, a common arrhythmia associated with increased morbidity and mortality. MATERIAL AND METHODS A retrospective cohort study was conducted involving 421 patients with non-valvular AF. Patients were classified based on the occurrence of adverse events, including hospitalization for heart failure, stroke, and all-cause mortality. Echocardiographic assessments of LAVI and RAVI were performed according to international guidelines. RESULTS Among the 421 patients, 180 (43%) experienced adverse events. Enlargement of both LAVI and RAVI was significantly associated with death, stroke, and heart failure (P<0.001). In multivariate analysis adjusted for age and sex, LAVI and RAVI were independent predictors of adverse outcomes. The presence of either LAVI or RAVI enlargement was associated with increased mortality (HR=1.96, 95% CI: 1.17-3.31), while the combined enlargement of both indices further increased the risk (HR=4.38, 95% CI: 2.71-7.08). Similar patterns were observed for stroke and heart failure, where the combination of both enlarged indices significantly amplified risk. CONCLUSIONS RAVI adds significant incremental prognostic value to LAVI in patients with AF. Combined assessment of both atrial volume indices enhances risk stratification for heart failure, stroke, and mortality, supporting more personalized treatment approaches in clinical practice.

Indexed as

Atrial FibrillationHeart AtriaAgedCohort StudiesEchocardiographyFemaleHeart FailureHumansMaleMiddle AgedPrognosisRetrospective StudiesRisk FactorsStroke

Identifiers

PMID40635251
PMCPMC12261965

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.