ArticleGlobalization and health2025
Understanding the political economy of reforming global health initiatives - insights from global and country levels.
Article in Globalization and health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Trends in demographic and health survey publications based on a bibliometric analysis.Global health action · 2026Pooled it
- Current status of cancer education in developing and developed countries: identifying the disparities and bridging the gap.Frontiers in public health · 2025Pooled it
- 'This is not our mandate': a qualitative case study on the resilience of a humanitarian health programme in Lebanon.Health policy and planning · 2026Article
- Instituting solidarity: the role of research institutes in advancing global health equity.Health research policy and systems · 2026Article
- Perspectives and Challenges of Healthcare Professionals, Patients, and Caregivers Regarding Utilizing Antibiotics and Implementing Antibiotic Stewardship in Healthcare Facilities in Low- and Middle-Income Countries: A Systematic Review of Qualitative Studies.Antibiotics (Basel, Switzerland) · 2026Review
- Back home, beyond borders: a bioecological study of returnee public health scholars in a globalized health system.Globalization and health · 2026Article
- Global Health Initiatives and Universal Health Coverage in Pakistan-Aligned for the Future?The International journal of health planning and management · 2026Article
- Research overview-2025: integrating scientific progress to accelerate global tuberculosis elimination.Frontiers in tuberculosis · 2026Article
- America First and Global Health Last: Assessing the Policy's Ripple Effects on Tropical Disease Control and Health Sovereignty in Sub-Sahara Africa.International journal of health policy and management · 2026Article
- Navigating power in policy adoption: The political economy of noncommunicable diseases in Sierra Leone.SSM - health systems · 2025Article
- Analysis of Health Systems Strengthening investment activities by Global Health Initiatives.BMC global and public health · 2025Article
- Health justice in fragile and shock-prone settings: from theory to practice towards building resilient health systems.BMJ global health · 2025Article
- Lenacapavir for HIV Prevention in Africa: Opportunities, Barriers, and Policy Priorities.Journal of the International Association of Providers of AIDS CareReview
Corrections and comments
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Authors and funding
19 authors.
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Abstract
introductionSince 2000, the number and role of global health initiatives (GHIs) has been growing, with these platforms playing an increasingly important role in pooling and disbursing funds dedicated to specific global health priorities. While recognising their important contribution, there has also been a growth in concerns about distortions and inefficiencies linked to the GHIs and attempts to improve their alignment with country health systems. There is a growing momentum to adjust GHIs to the current broader range of global health threats, such as non-communicable diseases, humanitarian crises and climate change, and against the backdrop of the recent aid cuts. However, reform attempts are challenged by the political economy of the current structures.
methodsIn this article, we draw on research conducted as part of the Future of Global Health Initiatives process. The study adopted a cross-sectional, mixed-methods approach, drawing from a range of data sources and data collection methods, including a global and regional level analysis as well as three embedded country case studies in Pakistan, South Africa and Senegal. All data was collected from February to July 2023. 271 documents were analysed in the course of the study, along with data from 335 key informants and meeting participants in 66 countries and across a range of constituencies. For this paper, data were analysed using a political economy framework which focused on actors, context (especially governance and financing) and framing.
findingsIn relation to actors, the GHIs themselves have become increasingly complex (both internally and in their interrelations with other global health actors and one another). They have a large range of clients (including at national level and amongst multilateral agencies) which function as collaborators as well as competitors. Historically there have been few incentives for any of the actors to maximise collaboration given the competitive funding landscape. Power to exert pressure for reforms sits ultimately with bilateral and private funders, though single-issue northern non-governmental organisations (NGOs) are also cited as important influencers. Funders have not collaborated to enable reforms, despite concerns amongst a number of them, because of the helpful functional role of GHIs, which serves funder interests. Some key global boards are reported to be engineered for stasis, and there are widespread concerns about lack of transparency and over-claiming (by some GHIs) of their results. Framing of narratives about achievements and challenges is important to enable or block reforms and are vigorously contested, with stakeholders often selecting different outcomes to emphasise in justifying positions.
conclusionGHIs have played an important role in the global health ecosystem but despite formal accountability structures to include recipient governments, substantive accountability has been focused upwards to funders, with risk management strategies which prioritise tracking resources more than improved national health system performance. Achieving consensus on reforms will be challenging but current funding pressures and new threats are creating a sense of urgency, which may shift positions. Political economy analysis can model and influence these debates.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.