Evidence map›Paper›PMID 40634931›Full record

Trial reportWorld journal of surgical oncology2025

Optimizing ERAS protocols in robotic nephron-sparing surgery: a randomized trial.

Yiqiang Wang, Mangmang He, Lulu Lou

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in World journal of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yiqiang WangHangzhou Hospital of Traditional Chinese Medicine, Hangzhou, Zhejiang Province, 310007, China.
Mangmang HeDepartment of the Operating Room, Affiliated People's Hospital, Zhejiang Provincial People's Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, 310014, China.
Lulu LouEmergency and Critical Care Center, Intensive Care Unit, Affiliated People's Hospital, Zhejiang Provincial People's Hospital, Hangzhou Medical College, No. 158 Shangtang Road, Gongshu District, Hangzhou, Zhejiang, 310014, China. llllllicu@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the clinical efficacy of evidence-based Enhanced Recovery After Surgery (ERAS) nursing protocols in patients undergoing robotic-assisted partial nephrectomy using the Da Vinci system.

methodsA total of 240 patients undergoing Da Vinci robot-assisted partial nephrectomy were randomized (1:1) to ERAS (n = 120) or conventional care (n = 120) groups using a stratified block randomization method. The sample size was calculated based on a power of 80%, α = 0.05, and anticipated clinically significant differences, though specific values for the standard deviation and effect size were not disclosed. Primary outcomes included operative time, estimated blood loss, and length of hospital stay. Secondary outcomes assessed complication rates (Clavien-Dindo classification) and patient-reported comfort (Kolcaba GCQ questionnaire). Categorical variables were analyzed using the Chi-square test, while continuous variables were assessed with the independent samples t-test. Bonferroni correction was applied for pairwise comparisons to control for multiple testing. All analyses adhered to the modified intention-to-treat principle using the full analysis set (FAS), and no imputation was made for missing data. A p-value < 0.05 was considered statistically significant.

resultsThe ERAS group demonstrated superior recovery metrics compared to the control group: operative duration (228.6 ± 9.5 vs. 252.8 ± 10.1 min, mean difference [MD] - 24.2, 95% CI -27.3, -21.1; p < 0.001), intraoperative blood loss (200.4 ± 18.2 vs. 232.6 ± 19.3 mL, MD - 32.2, 95% CI -36.8, -27.6; p < 0.001), and shorter postoperative milestones (ambulation: 14.3 ± 1.7 vs. 18.7 ± 2.2 h, p < 0.001; catheter removal: 2.1 vs. 3.5 days, p < 0.001). Hospital stay was significantly reduced (6.2 ± 2.1 vs. 10.5 ± 3.3 days, MD - 4.3, 95% CI -5.0, -3.6; p < 0.001). Complication rates were markedly lower with ERAS (14.2% vs. 39.2%, relative risk [RR] 0.36, 95% CI 0.24-0.55; p < 0.001), particularly for urinary infections (3.3% vs. 11.7%, p = 0.027) and wound hematomas (5.0% vs. 13.3%, p = 0.025). GCQ scores improved significantly in the ERAS group post-intervention (p < 0.001).

conclusionERAS nursing grounded in evidence-based medicine significantly enhances postoperative recovery, reduces complications, and improves patient comfort in robotic-assisted partial nephrectomy. These findings support its broader clinical adoption.

Indexed as

Enhanced Recovery After SurgeryKidney NeoplasmsNephrectomyNephronsOrgan Sparing TreatmentsPostoperative ComplicationsRobotic Surgical ProceduresAdultAgedBlood Loss, SurgicalFemaleFollow-Up StudiesHumansLength of StayMaleMiddle AgedDa Vinci surgical systemEnhanced recovery after surgeryKidney neoplasmsPartial nephrectomyPerioperative careRandomized controlled trialRobotic-assisted surgery

Identifiers

PMID40634931
PMCPMC12243225

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.