ArticleBMC public health2025
Vitamin A and D deficiencies in Tibetan vs. non-Tibetan children: roles of altitude, gender, and season in Sichuan Province.
Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- A Modular Digital FFQ for Tibetan Highlanders in Agricultural and Pastoral Communities: Development and Rigorous Multi-Method Validation.Nutrients · 2026Article
- Integrated omics reveal the effects of vitamin D deficiency on gut microbiota and plasma metabolism in experimental autoimmune uveitis.Journal of neuroinflammation · 2026Article
- A culturally integrated framework for infant nutrition beyond health education: lessons and a model from the Tibetan population.Frontiers in public health · 2026Review
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Abstract
backgroundVitamin deficiencies significantly impact children's growth and development, particularly in high-altitude regions. This study investigated the prevalence and patterns of vitamin A and D deficiencies among children in Tibetan versus non-Tibetan regions of Sichuan Province, China, considering the influences of altitude, gender, and seasonal variations.
methodsA case-control study was conducted comparing 995 Tibetan children from Garze Prefecture (altitude > 2000 m) with 995 age- and sex-matched non-Tibetan children from Luzhou City during 2017-2019. Vitamin A deficiency was defined as serum retinol < 0.70 µmol/L, and vitamin D deficiency as 25-hydroxyvitamin D < 50 nmol/L.
resultsTibetan children showed significantly higher rates of vitamin A (47.7% vs. 21.0%) and D (19.8% vs. 10.7%) deficiency compared to non-Tibetan children. Vitamin A and Vitamin D deficiency were more frequent in higher altitudes, with vitamin A (OR 5.2, 95% CI 2.44-11.09) and D deficiency (OR 2.47, 95% CI 1.28-4.77). Female Tibetan children demonstrated higher vitamin D deficiency risk, while summer and autumn were associated with lower vitamin D deficiency risk (OR 0.43, 95% CI 0.29-0.65).
conclusionsThis study reveals substantial disparities in vitamin A and D status between Tibetan and non-Tibetan children, with altitude, gender, and seasonal factors playing crucial roles. These findings emphasize the need for targeted nutritional interventions considering multiple environmental and demographic factors in high-altitude regions.
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