ArticleBMC pregnancy and childbirth2025
Association of discordant neonatal birth weight and maternal height with risk of preeclampsia: a multi-center retrospective cohort study in China.
Article in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Association of maternal height with pregnancy complications: Analyses of two cohorts.Pregnancy (Hoboken, N.J.) · 2026Article
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Abstract
backgroundUteroplacental mismatch contributes to development of preeclampsia, involving of reduced uteroplacental blood supply and/or increased fetoplacental demands. Maternal height and neonatal weight, which positively related to uteroplacental supply and fetoplacental demands were respectively shown to associated with altered risk of preeclampsia. However, data to comprehensively evaluate the integrated associations of neonatal weight and maternal height with the risk of preeclampsia is lacked.
methodsA respective cohort study was conducted among pregnant women delivered at 38 secondary or tertiary maternity centers in 14 cities of China during 2011 to 2012 to assess whether discordant neonatal birth weight and maternal height, such as tall mothers with small for gestational age (SGA) neonates or short mothers with large for gestational age (LGA) neonates, was associated with altered risk of preeclampsia. Short and tall heights were defined as ≤ 10
resultsThe study enrolled 88,673 women with singleton pregnancy. The overall incidence of preeclampsia was 2.69% and tall women delivering SGA neonates showed highest incidence (19.18%) (P < 0.01). Compared with women of average height delivering AGA neonates, women who gave birth to SGA neonates exhibited elevated preeclampsia risk across all height categories, with the most pronounced association observed among tall mother (adjusted OR 10.00, 95%CI 6.06-16.48). Short mothers delivering LGA infants showed a trend towards relatively higher incidence of preeclampsia compared to those of average height with AGA (3.24% vs. 2.35%, P = 0.65).
conclusionsThose tall women with SGA or short women with LGA are of elevated incidence of preeclampsia. Discordance of maternal height and fetal weight may be a potential indicator for high risk of preeclampsia.
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