Evidence map›Paper›PMID 40634874›Full record

ArticleBMC cardiovascular disorders2025

Effects of strict versus lenient rate control on exercise capacity in atrial fibrillation: a retrospective analysis.

Jinna Chang, Qian Du, Yuting Liu, Dujuan Li, Haofeng Zhou, Yingxue Liao, Junshuo Zhu, Bingqing Bai, Xiangyang Liu, Huan Ma

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Jinna Chang *Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, No. 106, Zhongshan Second Road, Yuexiu District, Guangzhou, Guangdong, 510080, China.
Qian Du *Department of Cardiology, Guangzhou Red Cross Hospital, Medical College, Jinan University, Guangzhou, 510240, China.
Yuting LiuThe Second Clinical College of Jinan University, Shenzhen People's Hospital, Shenzhen, 518055, China.
Dujuan LiDepartment of Rehabilitation Medicine, The Second Affiliated Hospital of Wannan Medical College, Wuhu, 241001, China.
Haofeng ZhouGuangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, No. 106, Zhongshan Second Road, Yuexiu District, Guangzhou, Guangdong, 510080, China.
Yingxue LiaoGuangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, No. 106, Zhongshan Second Road, Yuexiu District, Guangzhou, Guangdong, 510080, China.
Junshuo ZhuGuangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, China.
Bingqing BaiGuangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, China.
Xiangyang LiuDepartment of Cardiology, Yuebei People's Hospital Affiliated to Shantou University Medical College, No. 133, Huimin South Road, Wujiang District, Shaoguan, Guangdong, 512026, China. longliu0714@sina.com.
Huan MaGuangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, No. 106, Zhongshan Second Road, Yuexiu District, Guangzhou, Guangdong, 510080, China. mahuandoctor@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRate control is a primary treatment approach for managing atrial fibrillation (AF). However, a unified standard for the optimal level of control remains unestablished. This study aimed to investigate the impact of strict versus lenient heart rate control strategies on exercise capacity in patients with AF by assessing cardiopulmonary exercise test (CPET) results.

methodsA total of 693 patients with AF were included in this study. The patients were categorized into three groups on the basis of their resting heart rate: strict rate control (resting heart rate < 80 beats per minute and heart rate during moderate exercise < 110 beats per minute), lenient rate control (resting heart rate < 110 beats per minute), and uncontrolled rate (resting heart rate ≥ 110 beats per minute. CPET indicators were compared across the different rate control strategies, and trend analyses were conducted to explore whether there was a correlation between heart rate control and exercise capacity.

resultsSignificant differences in the maximum load, respiratory exchange ratio (RER), peak oxygen uptake (peak VO

conclusionIn patients with AF, strict heart rate control may enhance exercise capacity, suggesting the importance of effective heart rate management strategies.

Indexed as

Anti-Arrhythmia AgentsAtrial FibrillationExercise ToleranceHeart RateLungAgedExercise TestFemaleHumansMaleMiddle AgedOxygen ConsumptionRecovery of FunctionRetrospective StudiesTime FactorsTreatment OutcomeAnti-Arrhythmia AgentsAtrial fibrillationCardiopulmonary exercise testExercise capacityHeart rate controlPeak oxygen uptake

Identifiers

PMID40634874
PMCPMC12239340

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.