Evidence map›Paper›PMID 40634850›Full record

ArticleBMC nephrology2025

Determinants of dialysis adequacy in maintenance hemodialysis patients: a cross-sectional study on modifiable risk factors and clinical interventions.

Wanning Jia, Wenwen He, Zhuozhuo Chen, Haiyan Wang, Haitao Lu

Abstract read
In one paragraph

Article in BMC nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wanning JiaDepartment of Nephrology (Hemodialysis Center), China-Japan Friendship Hospital, Beijing, 100020, China.
Wenwen HeDepartment of Nephrology (Hemodialysis Center), China-Japan Friendship Hospital, Beijing, 100020, China.
Zhuozhuo ChenDepartment of Nephrology (Hemodialysis Center), China-Japan Friendship Hospital, Beijing, 100020, China.
Haiyan WangDepartment of Nephrology (Hemodialysis Center), China-Japan Friendship Hospital, Beijing, 100020, China.
Haitao LuDepartment of Nephrology (Hemodialysis Center), China-Japan Friendship Hospital, Beijing, 100020, China. lutao6677@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDialysis adequacy is crucial for maintaining the health and quality of life of patients undergoing maintenance hemodialysis (MHD). Assessing its current status and identifying influencing factors is essential for optimizing treatment outcomes. We aimed to evaluate the status of dialysis adequacy in MHD patients and analyze the factors that affect it.

methodsA cross-sectional study was conducted at a hemodialysis center from June to October 2024. A total of 232 MHD patients were included in the study. Data on demographics, hemodialysis parameters, and laboratory indicators were collected. Dialysis adequacy was assessed using the single pool Kt/V (spKt/V) method. Patients were categorized into adequate (spKt/V ≥ 1.2) and inadequate (spKt/V < 1.2) dialysis groups.

resultsOf the 232 patients, 147 (63.36%) had adequate dialysis. Factors significantly associated with dialysis adequacy included sex, age, dialysis duration, dry weight, vascular access type, ultrafiltration volume, β2-microglobulin levels, and oxygen supplementation (P < 0.05). Multiple linear regression analysis revealed that dialysis duration was an independent protective factor, whereas dry weight was an independent risk factor. These variables accounted for 79.30% of the variance in dialysis adequacy.

conclusionsDialysis adequacy in MHD patients requires further enhancement. Healthcare professionals can improve dialysis adequacy, ensure treatment efficacy, and enhance patients' quality of life by adjusting dry weight, administering continuous low-flow oxygen inhalation during dialysis, and managing interdialytic weight gain.

trial registrationCurrent Controlled Trials ISRCTN13609931, registered on 27 February 2025.

Indexed as

Kidney Failure, ChronicRenal DialysisAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedRisk FactorsDialysis adequacyDry weightHemodialysisInfluencing factorsOxygen inhalation

Identifiers

PMID40634850
PMCPMC12305990

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.