Evidence map›Paper›PMID 40634787›Full record

ArticleMolecular biology reports2025

Dietary supplementation with wholemeal bee powder (Apis mellifera) effect on improving metabolic parameters and modulating lipogenesis genes in diet-induced obese mice.

Joyce Hellyen Santos Pereira, Daniel Silva Moraes, Aline Lopes Nascimento, Bruna Kaicy Barbosa, Victor Hugo Dantas Guimarães, Junio Cota, Lucyana Conceição Farias, Alfredo Mauricio Batista de Paula, André Luiz Sena Guimarães, Sérgio Henrique Sousa Santos

Abstract read
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In one paragraph

Article in Molecular biology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Joyce Hellyen Santos PereiraHealth Science Laboratory, Postgraduate Program in Health Science, State University of Montes Claros (UNIMONTES), Montes Claros, MG, Brazil.ORCID http://orcid.org/0000-0002-2606-8850
Daniel Silva MoraesHealth Science Laboratory, Postgraduate Program in Health Science, State University of Montes Claros (UNIMONTES), Montes Claros, MG, Brazil.
Aline Lopes NascimentoInstitute of Agricultural Sciences (ICA), Postgraduate Program in Food and Health, Federal University of Minas Gerais (UFMG), Montes Claros, MG, Brazil.ORCID http://orcid.org/0000-0001-5528-4774
Bruna Kaicy BarbosaHealth Science Laboratory, Postgraduate Program in Health Science, State University of Montes Claros (UNIMONTES), Montes Claros, MG, Brazil.ORCID http://orcid.org/0009-0002-1603-833X
Victor Hugo Dantas GuimarãesHealth Science Laboratory, Postgraduate Program in Health Science, State University of Montes Claros (UNIMONTES), Montes Claros, MG, Brazil.ORCID http://orcid.org/0000-0002-4424-8142
Junio CotaInstitute of Agricultural Sciences (ICA), Postgraduate Program in Food and Health, Federal University of Minas Gerais (UFMG), Montes Claros, MG, Brazil.ORCID http://orcid.org/0000-0002-1547-4087
Lucyana Conceição FariasHealth Science Laboratory, Postgraduate Program in Health Science, State University of Montes Claros (UNIMONTES), Montes Claros, MG, Brazil.ORCID http://orcid.org/0000-0002-5379-361X
Alfredo Mauricio Batista de PaulaHealth Science Laboratory, Postgraduate Program in Health Science, State University of Montes Claros (UNIMONTES), Montes Claros, MG, Brazil.ORCID http://orcid.org/0000-0002-8715-0030
André Luiz Sena GuimarãesHealth Science Laboratory, Postgraduate Program in Health Science, State University of Montes Claros (UNIMONTES), Montes Claros, MG, Brazil.ORCID http://orcid.org/0000-0002-3162-3206
Sérgio Henrique Sousa SantosHealth Science Laboratory, Postgraduate Program in Health Science, State University of Montes Claros (UNIMONTES), Montes Claros, MG, Brazil. sergiosousas@hotmail.com.ORCID http://orcid.org/0000-0002-7788-5447

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity resulting from an energy imbalance is a key factor in the development of several comorbidities. Traditional communities have historically used insects for their nutritional and therapeutic benefits, particularly in treating chronic diseases such as diabetes and obesity. The present study explores the bee (Apis mellifera) powder supplementation effects on metabolic parameters in mice with diet-induced obesity. METHODS AND

resultsMale Swiss mice were subjected to a high-fat diet for three months, followed by a month of treatment with two different bee powder concentration additions. The animals were divided into four groups: standard diet, high-fat diet, high-fat with 15% bee powder, and high-fat with 30% bee powder. Bee powder supplementation reduced body weight and adipocyte size, promoting an increase in brown adipose tissue, decreasing glucose and cholesterol levels, and modulated the expression of FAS, ACC and GPX4.

conclusionThese findings suggest bee powder's potential use for therapeutic applications in treating obesity and related conditions.

Indexed as

Dietary SupplementsLipogenesisObesityPropolisAdipose Tissue, BrownAnimalsBeesBody WeightDiet, High-FatMaleMiceMice, ObesePowdersPowdersPropolisBee powderEdible insectsMetabolismObesityWeight loss

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.