Evidence map›Paper›PMID 40634784›Full record

ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2025

Genomic analysis of two all-stage stripe rust resistance genes in the Vavilov wheat landrace AGG40807WHEA1.

Raghvendra Sharma, Chunhong Chen, Peng Zhang, Hemlata Bharti, Venu Kumaran Vikas, Michael Norman, Katherine Dibley, Adnan Riaz, Tim Hewitt, Sami Hoxha and 6 more

Abstract read
In one paragraph

Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Raghvendra SharmaCommonwealth Scientific and Industrial Research Organization Agriculture and Food, Canberra, ACT, 2601, Australia.
Chunhong ChenCommonwealth Scientific and Industrial Research Organization Agriculture and Food, Canberra, ACT, 2601, Australia.
Peng ZhangPlant Breeding Institute, School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Cobbitty, NSW, 2570, Australia.
Hemlata BhartiCommonwealth Scientific and Industrial Research Organization Agriculture and Food, Canberra, ACT, 2601, Australia.
Venu Kumaran VikasCommonwealth Scientific and Industrial Research Organization Agriculture and Food, Canberra, ACT, 2601, Australia.
Michael NormanCommonwealth Scientific and Industrial Research Organization Agriculture and Food, Canberra, ACT, 2601, Australia.
Katherine DibleyCommonwealth Scientific and Industrial Research Organization Agriculture and Food, Canberra, ACT, 2601, Australia.
Adnan RiazCentre for Crop Science, Queensland Alliance for Agriculture and Food Innovation, The University of Queensland, Brisbane, QLD, 4072, Australia.
Tim HewittCommonwealth Scientific and Industrial Research Organization Agriculture and Food, Canberra, ACT, 2601, Australia.
Sami HoxhaPlant Breeding Institute, School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Cobbitty, NSW, 2570, Australia.
Kerrie ForrestAgriBio, Centre for AgriBioscience, Department of Energy, Environment and Climate Action, Bundoora, VIC, 3083, Australia.
Evans LagudahCommonwealth Scientific and Industrial Research Organization Agriculture and Food, Canberra, ACT, 2601, Australia.
Harbans BarianaPlant Breeding Institute, School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Cobbitty, NSW, 2570, Australia.
Urmil BansalPlant Breeding Institute, School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Cobbitty, NSW, 2570, Australia.
Lee HickeyCentre for Crop Science, Queensland Alliance for Agriculture and Food Innovation, The University of Queensland, Brisbane, QLD, 4072, Australia. l.hickey@uq.edu.au.
Sambasivam PeriyannanCommonwealth Scientific and Industrial Research Organization Agriculture and Food, Canberra, ACT, 2601, Australia. sambasivam.periyannan@unisq.edu.au.ORCID http://orcid.org/0000-0002-5421-2872

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

key messageComparative genomic analysis of two all-stage stripe rust resistance loci from Vavilov wheat landrace accession, AGG40807WHEA1, using Chinese Spring and 10 + hexaploid wheat genomes and validation of closely linked KASP markers. The ongoing occurrence and spread of wheat stripe rust, caused by the fungal pathogen Puccinia striiformis f. sp. tritici, threatens the global food security. Cultivation of varieties with effective sources of resistance is often followed by the appearance of virulent pathotypes at various times after their introduction. This requires an ongoing search for new sources. Tests of 296 accessions from the Vavilov wheat landrace collection identified numerous lines with broadly effective all-stage stripe rust resistance. Genetic analysis of one of these accessions (Australian Grains Genebank number AGG40807WHEA1) identified two all-stage resistance genes, temporarily named YrV1 and YrV2. The YRV1 and YRV2 loci were mapped to 3.48-3.98 and 730.2-731.2 Mb intervals in the short arm of chromosome 3B and the long arm of chromosome 7B, respectively. A comparative genomic analysis of the YRV1 locus in the Chinese Spring and the 10 + wheat pangenome databases revealed genomic rearrangements and lack of sequences encoding a nucleotide-binding and leucine-rich repeat (NLR) domain protein. Sequences belonging to NLR-like genes were present in the YRV2 region. Kompetitive allele-specific PCR (KASP) markers designed from SNPs IWB71814 and IWB69562, located at 0.4 cM and 0.5 cM distal to YrV1 and YrV2, respectively, were validated for marker-assisted selection using 123 hexaploid and 15 tetraploid wheat and 14 triticale cultivars. YrV1 and YrV2 genes are potentially valuable resources, and use of the closely linked molecular markers will expedite their deployment in breeding.

Indexed as

Disease ResistanceGenes, PlantPlant DiseasesTriticumBasidiomycotaChromosome MappingChromosomes, PlantGenetic MarkersPolymorphism, Single NucleotidePucciniaGenetic Markers

Identifiers

PMID40634784
PMCPMC12241163

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.