Evidence map›Paper›PMID 40634755›Full record

ArticleNature materials2025

Encoding hierarchical 3D architecture through inverse design of programmable bonds.

Jason S Kahn, Brian Minevich, Aaron Michelson, Hamed Emamy, Jiahao Wu, Huajian Ji, Alexia Yun, Kim Kisslinger, Shuting Xiang, Nanfang Yu and 2 more

Abstract read
In one paragraph

Article in Nature materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Hierarchical Assembly of Multilayer Core-Shell DNA Origami Crystals.Advanced materials (Deerfield Beach, Fla.) · 2026
    Article
  3. Article
  4. Review
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  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jason S Kahn *Department of Chemical Engineering, Columbia University, New York, NY, USA.ORCID http://orcid.org/0000-0002-6330-1703
Brian Minevich *Department of Chemical Engineering, Columbia University, New York, NY, USA.
Aaron MichelsonCenter for Functional Nanomaterials, Brookhaven National Laboratory, Upton, NY, USA.ORCID http://orcid.org/0000-0003-3060-3788
Hamed EmamyDepartment of Chemical Engineering, Columbia University, New York, NY, USA.ORCID http://orcid.org/0000-0002-5078-5569
Jiahao WuDepartment of Applied Physics and Applied Mathematics, Columbia University, New York, NY, USA.ORCID http://orcid.org/0009-0009-5757-4797
Huajian JiDepartment of Chemical Engineering, Columbia University, New York, NY, USA.
Alexia YunDepartment of Chemical Engineering, Columbia University, New York, NY, USA.
Kim KisslingerCenter for Functional Nanomaterials, Brookhaven National Laboratory, Upton, NY, USA.
Shuting XiangDepartment of Chemical Engineering, Columbia University, New York, NY, USA.
Nanfang YuDepartment of Applied Physics and Applied Mathematics, Columbia University, New York, NY, USA.ORCID http://orcid.org/0000-0002-9462-4724
Sanat K KumarDepartment of Chemical Engineering, Columbia University, New York, NY, USA.ORCID http://orcid.org/0000-0002-6690-2221
Oleg GangDepartment of Chemical Engineering, Columbia University, New York, NY, USA. og2226@columbia.edu.ORCID http://orcid.org/0000-0001-5534-3121

Funding

DOE | SC | Basic Energy Sciences (BES) DE-SC0008772DOE | SC | Basic Energy Sciences (BES) DE-SC0012704
6 · The paper itself

Abstract

The ability to fabricate materials and devices at small scales by design has resulted in tremendous technological progress. However, the need for engineered three-dimensional (3D) nanoscale materials requires new strategies for organizing nanocomponents. Here we demonstrate an inverse design approach for the assembly of nanoparticles into hierarchically ordered 3D organizations using DNA voxels with directional, addressable bonds. By identifying intrinsic symmetries in repeating mesoscale structural motifs, we prescribe a set of voxels, termed a mesovoxel, that are assembled into target 3D crystals. The relationship between different degrees of encoded information used for voxel bonds and the fidelity of assembly is investigated using experimental and computational methods. We apply this assembly strategy to create periodic 3D nanoparticle ordered organizations, including structures with low-dimensional elements, helical motifs, a nanoscale analogue of a face-centred perovskite crystal and a distributed Bragg reflector based on a crystal with plasmonic and photonic length-scale regimes.

Identifiers

PMID40634755
PMCPMC12310530

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.