ArticleNature human behaviour2025
Unattended working memory items are coded by persistent activity in human medial temporal lobe neurons.
Article in Nature human behaviour, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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Who cites it
3 citing papers in PubMed.
- Article
- Human Beta Oscillations Reflect Magnitude and Fidelity of Priority Shifts in Working Memory.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Brain-wide single-neuron bases of working memory for sounds in humans.bioRxiv : the preprint server for biology · 2025Article
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
The role of persistent neural activity in working memory storage is well documented, particularly in tasks where memorized items are of equal importance. However, the encoding mechanism for unattended items, often considered as 'activity silent', remains poorly understood. Here we recorded the activity of image-selective neurons in the medial temporal lobe while subjects (n = 12) shifted attention between concurrently stored memory items. Our results demonstrate that both attended and unattended memory items are encoded through persistent activity. Additionally, we observed a dynamic transformation in the neuronal subspace following cue presentation, reflecting a shift in how information was maintained. While information about the unattended item was decodable at the single-trial level from preselected image-selective cells, it was not decodable from the entire population of medial temporal lobe cells. These findings support models of persistent activity and challenge the notion that unattended items are stored via 'activity-silent' mechanisms.
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