Evidence map›Paper›PMID 40634535›Full record

ArticleScientific reports2025

Lactiplantibacillus plantarum dfa1 reduces obesity caused by a high carbohydrate diet by modulating inflammation and gut microbiota.

Thunnicha Ondee, Krit Pongpirul, Lampet Wongsaroj, Sayamon Senaprom, Suphot Wattanaphansak, Asada Leelahavanichkul

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Journal of microbiology and biotechnology · 2026
    Article
  3. Article
  4. Article
  5. [Comparative Analysis of Oral and Gut Microbiota Composition in Children Aged 3-5 Years With Different Body Mass Indexes in Urumqi].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Thunnicha OndeeDepartment of Preventive and Social Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand.
Krit PongpirulDepartment of Preventive and Social Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand. doctorkrit@gmail.com.
Lampet WongsarojPorcinotec Co.,Ltd., Tiwanont Road, Tambon Talat Khwan, Amphur Mueang, Nonthaburi, Thailand.
Sayamon SenapromDepartment of Preventive and Social Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand.
Suphot WattanaphansakDepartment of Veterinary Medicine, Faculty of Veterinary Science, Chulalongkorn University, Pathum Wan, Bangkok, Thailand.
Asada LeelahavanichkulDepartment of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand. a_leelahavanit@yahoo.com.

Funding

Second Century Fund (C2F) N/AThailand Science Research and Innovation Fund Chulalongkorn University FOODF67300006
6 · The paper itself

Abstract

Given the potential of probiotics to counteract obesity induced by high glucose diets (HGD) and the beneficial effects of high-fiber diets, this study explored the impact of Lactiplantibacillus plantarum dfa1 (Lp dfa1) in mice consuming modified diets, including a unique high-carbohydrate biscuit diet (HBD) featuring Prachuap Khiri Khan's Pineapple Cheese Cake Biscuit for its rich fiber content. Notably, the fruit-derived soluble fiber HBD might have a synbiotic effect (the enhanced beneficial bacteria in the gut) different from HGD. in The standard mouse diet (RD) with a carbohydrate: protein: fat (C: P:F) ratio of 56:13:31 served as the base, which was then modified with either glucose to form the HGD (C: P:F at 60:25:15) or blended with the high-fiber dessert to create the HBD (C: P:F at 70:9:21). Over 12 weeks, mice were fed HGD or HBD with and without daily oral administration of Lp dfa1 at 1 × 10

Indexed as

Dietary CarbohydratesGastrointestinal MicrobiomeInflammationLactobacillaceaeObesityProbioticsAnimalsMaleMiceMice, Inbred C57BLDietary CarbohydratesGlucoseLactiplantibacillus plantarumObesityPrediabetesSugar

Identifiers

PMID40634535
PMCPMC12241623

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.