ArticleScientific reports2025
Synthesize, antioxidant and antimicrobial properties of a chitosan xerogel film with Nigella Sativa extract.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Development of Nigella sativa essential oil loaded keratin/gelatin cryogel with antimicrobial and antioxidant properties for wound dressing.Scientific reports · 2026Article
- Harnessing Polymeric Xerogels for Enhanced Wound Care: Properties, Mechanisms, and Applications.ACS materials Au · 2026Review
- Antimicrobial and Antioxidant Effects of Aqueous, Methanolic, and a Deep Eutectic Solvent-Based Extracts ofScientifica · 2026Article
- Hydrogel Films in Biomedical Applications: Fabrication, Properties and Therapeutic Potential.Gels (Basel, Switzerland) · 2025Review
- Topical Delivery Systems for Plant-Derived Antimicrobial Agents: A Review of Current Advances.International journal of biomaterials · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
The prevalence rates of microbial infections in wounds present a medical challenge, as damaged skin is inherently more susceptible to colonization/infection by pathogens. Deep eutectic solvents are a type of environmentally friendly cost-effective, and efficient solvent used in the extraction of bioactive compounds from plant materials. The study investigates the preparation of a xerogel formulation incorporating Nigella sativa extract, utilizing deep eutectic solvents that comprise chitosan and gallic acid-grafted gelatin, with the potential to enhance wound healing through antimicrobial and antioxidant actions. The xerogel has been evaluated for physicochemical characteristics by using Fourier transform infrared spectroscopy, scanning electron microscopy, and different chemical analyses. Mechanical properties of the film has confirmed that this formulation would be suitable for dressing wounds that require conformability. It is indicated from the disk diffusion test that the film showed efficacy in inhibition of Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, and Candida albicans. Preliminary studies have shown this formulation has structural integrity, a cell-friendly nature, is remarkably antioxidant-active, and exhibited antimicrobial activity hence possibly application in pharmaceutical fields. The results will add to our understanding of how DES can effectively be used in enhancing the bioactivity of natural extracts in polymeric matrices and help pave a way for advanced applications in health-related products.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.