Evidence map›Paper›PMID 40634464›Full record

ArticleScientific reports2025

Depression impact on PTSD in Cancer patients through serial mediation of hope and perceived social support.

Chen Zhang, Jingjing Wang, Yunhui He, Kaili Wang, Chonghan Wang, Luxiang Zhang, Xiaofei Wu, Shuangquan Liang, Xiaoyan Wu, Yujie Wei and 2 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Chen Zhang *School of Mental Health, Bengbu Medical University, Bengbu, 233030, Anhui, China.
Jingjing Wang *School of Mental Health, Bengbu Medical University, Bengbu, 233030, Anhui, China.
Yunhui He *School of Mental Health, Bengbu Medical University, Bengbu, 233030, Anhui, China.
Kaili WangSchool of Mental Health, Bengbu Medical University, Bengbu, 233030, Anhui, China.
Chonghan WangSchool of Mental Health, Bengbu Medical University, Bengbu, 233030, Anhui, China.
Luxiang ZhangSchool of Mental Health, Bengbu Medical University, Bengbu, 233030, Anhui, China.
Xiaofei WuSchool of Mental Health, Bengbu Medical University, Bengbu, 233030, Anhui, China.
Shuangquan LiangSchool of Mental Health, Bengbu Medical University, Bengbu, 233030, Anhui, China.
Xiaoyan WuSchool of Mental Health, Bengbu Medical University, Bengbu, 233030, Anhui, China.
Yujie WeiSchool of Mental Health, Bengbu Medical University, Bengbu, 233030, Anhui, China.
Mingjie ZhangSchool of Mental Health, Bengbu Medical University, Bengbu, 233030, Anhui, China. 24393313@qq.com.
Wenjuan WangSchool of Mental Health, Bengbu Medical University, Bengbu, 233030, Anhui, China. wwj.wen@163.com.

Funding

Anhui Province Graduate Student Innovation and Practice Research Project No.2023cxcysj160China Student Innovation Training Program Project Project No.S202310367126Ideological and Political Education Demonstration Project of Anhui Province Quality Project of Higher Education Institutions Project No.2022kcsz188Provincial Education Department Natural Science Key Project No.2022AH051512, 2022AH051430
6 · The paper itself

Abstract

Previous studies have only established a strong association between depression and post-traumatic stress disorder in cancer patients, without clarifying the potential mechanisms underlying this relationship. This study examines the relationship between depression and PTSD(Post-Traumatic Stress Disorder) in cancer patients, focusing on the sequential mediation of hope and perceived social support. A cross-sectional study was conducted at oncology wards in an Anhui tertiary hospital between February-August 2024. The investigation employed four instruments: PTSD checklist-civilian version, self-rating depression scale, perceived social support scale, and herth hope index. Analysis included 192 cancer patients, after removing 8 invalid responses from 200 initial participants. Treating depression as the predictor variable in cancer patients revealed a robust association with PTSD symptoms. (β = 0.620, t = 10.904, p < 0 0.001, R

Indexed as

DepressionHopeNeoplasmsSocial SupportStress Disorders, Post-TraumaticAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedCancerDepressionHopePerceived social supportPost-traumatic stress disorder

Identifiers

PMID40634464
PMCPMC12241477

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.