Evidence map›Paper›PMID 40634456›Full record

ArticleScientific reports2025

Mucosal immune response in pigs following the primary and secondary exposure to porcine epidemic diarrhea virus genogroups G1 and G2.

Patumporn Jermsutjarit, Gun Temeeyasen, Kepalee Saeng-Chuto, Parin Watcharavongtip, Pablo Piñeyro, Hongyao Lin, Kampon Kaeoket, Angkana Tantituvanont, Dachrit Nilubol

Abstract read
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In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Patumporn JermsutjaritDepartment of Veterinary Microbiology, Faculty of Veterinary Science, Chulalongkorn University, Henry Dunant Road, Pathumwan, Bangkok, 10330, Thailand.
Gun TemeeyasenAnimal Disease Research and Diagnostic Laboratory, Department of Veterinary and Biomedical Sciences, South Dakota State University, Brookings, SD, 57007, USA.
Kepalee Saeng-ChutoDepartment of Biological Sciences, University of Nebraska-Lincoln, Lincoln, NE, 68583- 0900, USA.
Parin WatcharavongtipDepartment of Veterinary Microbiology, Faculty of Veterinary Science, Chulalongkorn University, Henry Dunant Road, Pathumwan, Bangkok, 10330, Thailand.
Pablo PiñeyroDepartment of Veterinary Diagnostic and Production Animal Medicine, Iowa State University College of Veterinary Medicine, Ames, IA, 50011, USA.
Hongyao LinMSD Animal Health Innovation Pte Ltd., Perahu Road, Singapore, 718847, Singapore.
Kampon KaeoketDepartment of Clinical Sciences and Public Health, Faculty of Veterinary Science, Mahidol University, Nakhonpathom, 73170, Thailand.
Angkana TantituvanontDepartment of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, 10330, Thailand.
Dachrit NilubolDepartment of Veterinary Microbiology, Faculty of Veterinary Science, Chulalongkorn University, Henry Dunant Road, Pathumwan, Bangkok, 10330, Thailand. dachrit@gmail.com.

Funding

National Research Council of Thailand N41A640366
6 · The paper itself

Abstract

This study was conducted to evaluate cellular and humoral mucosal immune responses of pigs infected with porcine epidemic diarrhea virus (PEDV) genogroups 1 (G1) or 2 (G2). Anamnestic response following homologous or heterologous reinfection were also investigated. Forty-five PEDV-negative, 3-week-old pigs were allocated into 3 groups of 15 pigs each. Pigs were orally inoculated with EAS1 (G1) or CBR1 (G2) or cell culture supernatant and serially monitored for PEDV-specific IFN-γ producing cells (IFN-γ PC) and IgA antibody secreting cells (ASC). Three pigs served as baseline at day 0. The CD4

Indexed as

Coronavirus InfectionsImmunity, MucosalPorcine epidemic diarrhea virusSwine DiseasesAnimalsAntibodies, ViralCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesImmunoglobulin AInterferon-gammaSwineAntibodies, ViralImmunoglobulin AInterferon-gammaMucosal immunityPEDV genogroupSecondary exposure

Identifiers

PMID40634456
PMCPMC12241416

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.