Evidence map›Paper›PMID 40634093›Full record

ArticleInternal medicine (Tokyo, Japan)2026

Fibrotic Pulmonary Sarcoidosis with Honeycomb-like Changes Mimicking Idiopathic Pulmonary Fibrosis/Usual Interstitial Pneumonia (IPF/UIP) in the Lower Lobes: A Case Treated with Anti-fibrotic Therapy.

Takeshi Kawanobe, Tetsuo Yamaguchi, Yuho Ishida, Michiru Sawahata, Takeshi Johkoh, Chiyoko Kono, Noriharu Shijubo, Tamiko Takemura, Satoshi Konno

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Histopathologic overlap between fibrotic sarcoidosis and UIP pattern.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Takeshi KawanobeDepartment of Respiratory Medicine, JR Tokyo General Hospital, Japan.
Tetsuo YamaguchiDepartment of Respiratory Medicine, Shinjuku Tsurukame Clinic, Japan.
Yuho IshidaDepartment of Respiratory Medicine, JR Tokyo General Hospital, Japan.
Michiru SawahataDivision of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Japan.
Takeshi JohkohDepartment of Radiology, Kansai Rosai Hospital, Japan.
Chiyoko KonoDepartment of Respiratory Medicine, JR Tokyo General Hospital, Japan.
Noriharu ShijuboDepartment of Respiratory Medicine, JR Sapporo Hospital, Japan.
Tamiko TakemuraDepartment of Pathology, Kanagawa Cardiovascular and Respiratory Center, Japan.
Satoshi KonnoDepartment of Respiratory Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Established fibrosis in pulmonary sarcoidosis is typically not progressive. However, progressive fibrosis similar to interstitial pneumonia occasionally occurs. We herein report a 49-year-old woman who was histologically diagnosed with sarcoidosis. She also had honeycomb-like manifestations in the lower lobes that resembled idiopathic pulmonary fibrosis on computed tomography, whereas pathological findings of a surgical lung biopsy suggested interstitial lung disease associated with rheumatoid arthritis. However, the patient did not develop clinical rheumatoid arthritis even after 17 years of follow-up. Notably, she showed progressive fibrosis and was treated with anti-fibrotic therapy. It is thus important to recognize progressive fibrosis in pulmonary sarcoidosis, although it is rare.

Indexed as

Antifibrotic AgentsIdiopathic Pulmonary FibrosisSarcoidosis, PulmonaryDiagnosis, DifferentialFemaleHumansMiddle AgedTomography, X-Ray ComputedAntifibrotic Agentsanti-fibrotic drugsfibrotic pulmonary sarcoidosisprogressive fibrosing interstitial lung diseasesarcoidosis

Identifiers

PMID40634093
PMCPMC12945428

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.