Evidence map›Paper›PMID 40633616›Full record

ArticleThe Journal of nutrition2025

Alcohol Consumption and Melanoma in a Prospective United States Cohort Study: Results from the NIH-AARP Diet and Health Study.

Briana Roberts, Megan Hoang, Ju-Woo Nho, Yufei Li, Linda M Liao, Rashmi Sinha, Abrar A Qureshi, Eunyoung Cho

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Article in The Journal of nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Briana RobertsDepartment of Epidemiology, Brown School of Public Health, Providence, RI, United States.
Megan HoangWarren Alpert Medical School, Brown University, Providence, RI, United States.
Ju-Woo NhoBrown University, Providence, RI, United States.
Yufei LiDepartment of Epidemiology, Brown School of Public Health, Providence, RI, United States.
Linda M LiaoDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, United States.
Rashmi SinhaDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, United States.
Abrar A QureshiDepartment of Epidemiology, Brown School of Public Health, Providence, RI, United States; Department of Dermatology, Warren Alpert Medical School, Brown University, Providence, RI, United States.
Eunyoung ChoDepartment of Epidemiology, Brown School of Public Health, Providence, RI, United States; Department of Dermatology, Warren Alpert Medical School, Brown University, Providence, RI, United States; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States. Electronic address: eunyoung_cho@brown.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlcohol consumption is a modifiable lifestyle factor linked with multiple forms of cancer. There is a relative paucity of prospective data on the associations between alcohol consumption and melanoma subtypes.

objectivesIn this study, we investigated the associations of total alcohol consumption and different types of alcoholic beverages on risk of malignant melanoma (MM) and melanoma in situ (MIS) among 469,828 participants of the National Institutes of Health-American Association of Retired Persons (NIH-AARP) Diet and Health Study.

methodsAlcoholic beverage consumption, to include beer, wine, and liquor consumption, in the past year was assessed at baseline by questionnaire and defined as a categorical variable. Total melanoma included MM and MIS. Multivariable-adjusted Cox proportional hazards regressions were used to calculate the hazard ratios (HRs) and 95% confidence intervals (CIs).

resultsDuring 6,297,881 person-years of follow-up with a median of 15.5 y, 5034 cases of MM and 3284 cases of MIS were identified. Higher total alcohol consumption was associated with an elevated risk of melanoma; the HR for total melanoma was 1.17 (95% CI: 1.07, 1.28) for those who consumed >3 drinks/d compared with nondrinkers (P

conclusionsOur results suggest that alcohol consumption was associated with an increased risk of melanoma, including both MM and MIS.

Indexed as

alcoholcancer epidemiologyCox regressionmelanomaprospective study

Identifiers

PMID40633616
PMCPMC12799453

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