Evidence map›Paper›PMID 40633577›Full record

ArticlePsychiatry investigation2025

Mediating Effect of Psychological Inflexibility, Insomnia, and Resilience on the Association Between Pain and Depression Among Patients With Chronic Pain.

Hussein Makhour, Seockhoon Chung

Abstract read
In one paragraph

Article in Psychiatry investigation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hussein MakhourFaculty of Medical Sciences, Lebanese University, Beirut, Lebanon.
Seockhoon ChungDepartment of Psychiatry, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveChronic pain, impacting roughly 20% of the population, significantly affects quality of life and productivity. This study explored the mediating effects of psychological inflexibility, insomnia, and resilience on the association between pain and depression in patients with chronic pain.

methodsData on demographics, pain characteristics, and psychological factors were obtained through an online survey involving 100 patients from the Asan Medical Center Pain Clinic. Measures included the Patient Health Questionnaire-9, Insomnia Severity Index (ISI), Acceptance and Action Questionnaire-II (AAQ-II), and Brief Resilience Scale (BRS). Statistical analyses involved correlation, linear regression, and mediation analyses.

resultsA linear regression analysis revealed that the severity of depression was predicted by pain severity (β=0.18, p=0.018), ISI (β=0.22, p=0.010), AAQ-II (β=0.32, p<0.001), and BRS (β=-0.28, p=0.002). The mediation analysis showed that pain severity directly influenced depression severity. This relationship was partially mediated by ISI, AAQ-II, and BRS.

conclusionThis study underscores the necessity for holistic approaches in chronic pain management that address the mediating effect of psychological factors. Targeted interventions focusing on insomnia, psychological inflexibility, and resilience can significantly enhance mental health outcomes for patients with chronic pain.

Indexed as

Chronic painDepressionInsomniaPsychological inflexibilityResilience

Identifiers

PMID40633577
PMCPMC12301685

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.