ArticleScience advances2025
Integrating population genomics and environmental data to predict adaptation to climate change in post-bottleneck Tibetan macaques.
Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Low-pass whole-genome sequencing reveals genomic diversity and ecotype-specific adaptation in indigenous Tigrayan chickens.Scientific reports · 2026Article
- Genomic-Environmental Integration Predicts Climate Vulnerability and Adaptive Potential of Tibetan Plateau Herpetofauna.Integrative zoology · 2026Article
- Modeling the effects of climate risk on primates globally: New perspectives on conservation priorities.Science advances · 2026Article
- Population Genomics Highlight the Vulnerability of Coral-Dwelling Gobies to Ecological Losses due to Climatic Disturbances.Molecular ecology · 2026Article
- A Genomic Method for Combating Wildlife Trafficking: SNP-Based Traceability of Four Endangered Species in China.Animals : an open access journal from MDPI · 2026Article
- Genomics Insights Into High-Latitude Adaptation of Tibetan Macaques.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Demographic history and identification of threats under climate and anthropogenic activity provide insights into conservation for Cypripedium palangshanense.BMC plant biology · 2026Article
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Authors and funding
13 authors.
Funding
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Abstract
Rapid climate change represents a profound threat to biodiversity. Understanding the local adaptations and their vulnerabilities to climate change are imperative for developing conservation measures. Here, we combined a multidisciplinary approach to determine the local adaptations of an endemic and near-threatened primate, aiming to reveal its potential to cope with future climate change. Results suggest that climatic fluctuations played an important role in shaping its demographic trajectory and genetic structure. In addition, Tibetan macaques have experienced a severe bottleneck in the recent past, with highly deleterious mutations partially removed, but moderately deleterious mutations accumulating. The severe bottleneck and lower genetic diversity may have reduced their potential to adapt to environmental change, which will compromise long-term viability. Furthermore, we found that the eastern group exhibited higher genomic offsets and loss of suitable habitat in response to climate change. Overall, we emphasize the importance of integrating population genomics and environmental data to predict the adaptation of post-bottleneck populations to rapid climate change.
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