ArticlePloS one2025
From diverticulum to diagnosis: The distinctive role of Endoscopic Ultrasonography in Lemmel syndrome.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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4 authors.
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Abstract
BACKGROUND AND
aimLemmel syndrome is a rare cause of obstructive jaundice, induced by periampullary diverticulum(PAD). Endoscopic Ultrasonography(EUS) is helpful in detecting PAD and differentiating the obstruction cause in Lemmel syndrome by exposing the detail of ampulla structure and measuring the dilatation of common bile duct and pancreatic duct. MATERIALS AND
methodsNineteen patients diagnosed Lemmel syndrome by EUS in our institute between January 1, 2019 to April 30, 2024 were enrolled. Their demographics, laboratory and imaging data were analyzed.
resultsThe patients diagnosed with Lemmel syndrome were mostly elder male with the average age of 68.8 ± 2.4 years. We found Lemmel syndrome patients most present with a dilatation in middle and upper segments of common bile duct. Magnetic resonance cholangiopancreatography (MRCP), abdominal computed tomography (CT) and upper abdominal enhanced MR were all failed to diagnose Lemmel syndrome. Besides, a higher serum level of alkaline phosphatase was predominant in those complicating with cholecystitis or cholecystolithiasis than those without complications.
conclusionsSimilar with non-invasive imaging examination, EUS was capable of confirming the diagnosis of Lemmel syndrome, evaluating PAD and pancreaticobiliary duct as well as periampullary structure. EUS could be a useful investigate method to distinguish Lemmel syndrome for patients with unexplained dilated common bile duct or jaundice.
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