ArticleObesity surgery2025
In-Hospital Outcomes of Bariatric Surgery in People Living with HIV: A Nationwide Analysis.
Article in Obesity surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Impact of Bariatric Surgery on Post-Transplant Outcomes in Solid Organ Recipients: A Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- Methodological and Data Reporting Concerns in "In-Hospital Outcomes of Bariatric Surgery in People Living with HIV".Obesity surgery · 2026Article
- Letter to the Editor Regarding: "In-Hospital Outcomes of Bariatric Surgery in People Living with HIV: A Nationwide Analysis".Obesity surgery · 2025Article
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9 authors.
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Abstract
backgroundBariatric surgery is a growing treatment for Class 3 obesity in people with HIV, but concerns remain about antiretroviral therapy pharmacokinetics, comorbidities, and mortality. Existing studies confirm safety but are limited by small sample sizes and outdated cohorts. This study utilizes a recent, large U.S. inpatient cohort to address gaps.
methodsWe performed a retrospective cohort study using the Nationwide Inpatient Sample from 2015 to 2021, identifying hospitalizations for bariatric surgery among patients with and without HIV. We compared demographics, comorbidities, and hospitalization outcomes between groups. We analyzed in-hospital mortality using Weibull regression and identified independent predictors via multivariable Cox proportional hazards models.
resultsOf 112,348 bariatric surgery hospitalizations, 1,204 (1.1%) were in HIV-positive patients. HIV-positive patients were younger (51.0 vs. 56.1 years; p < 0.001), predominantly male (72.0% vs. 40.3%; p < 0.001), and had longer median lengths of stay (14.2 vs. 10.7 days; p < 0.001). Bariatric surgery rates among HIV-positive patients remained stable from 2017 to 2021 (p = 0.4). Compared with HIV-negative patients, those with HIV had higher prevalences of liver disease (11.7% vs. 1.7%; p < 0.001), renal disease (12.7% vs. 9.2%; p < 0.001), and a history of cancer (26.3% vs. 15.7%; p < 0.001). In unadjusted Weibull regression, HIV-positive status was associated with better in-hospital survival (p = 0.001), but after adjustment, HIV was not an independent predictor of mortality (HR 0.97; p = 0.843). Independent predictors of mortality across the entire cohort included advancing age (HR 1.04 per year; p < 0.001), sepsis (HR 3.36; p < 0.001), and liver disease (HR 1.70; p < 0.001).
conclusionBariatric surgery is safe for HIV-positive patients. Despite stable utilization, disparities persist. Further research is needed to improve access and assess long-term outcomes.
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