Evidence map›Paper›PMID 40632389›Full record

ArticleGeneral thoracic and cardiovascular surgery2026

Analysis of risk factors for postoperative infections following the Nuss procedure for pectus excavatum.

Atsushi Higashio, Yoshiki Morotomi, Yumi Mizoue, Kenichi Saga, Masakatsu Takeda, Mari Sonoda, Tamaki Iwade, Kosuke Endo, Hiroaki Fukuzawa, Masahito Sato

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Article in General thoracic and cardiovascular surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Atsushi HigashioDepartment of Pediatric Surgery, Medical Research Institute Kitano Hospital, 2-4-20, Ogi-Machi, Kita-Ku, Osaka, Osaka, 540-8480, Japan. a-higashio@kitano-hp.or.jp.ORCID http://orcid.org/0000-0003-1485-4181
Yoshiki MorotomiYagi Clinic, 1-4-3, Adachi, Suminoe-Ku, Osaka, Osaka, 559-0003, Japan.
Yumi MizoueDepartment of Pediatric Surgery, Medical Research Institute Kitano Hospital, 2-4-20, Ogi-Machi, Kita-Ku, Osaka, Osaka, 540-8480, Japan.
Kenichi SagaDepartment of Surgery, Graduate School of Medicine, Kyoto University, Syoshida-Konoe-Cho, Sakyo-Ku, Kyoto, Kyoto, 606-8507, Japan.
Masakatsu TakedaDepartment of General Surgery, Kyoto City Hospital, 1-2, Mibuhigashi-Tadkada-Cho, Nakagyo-Ku, Kyoto, Kyoto, 604-8845, Japan.
Mari SonodaDepartment of Pediatric Surgery, Medical Research Institute Kitano Hospital, 2-4-20, Ogi-Machi, Kita-Ku, Osaka, Osaka, 540-8480, Japan.
Tamaki IwadeDepartment of Pediatric Surgery, Ishikawa Prefectural Central Hospital, 2-1, Kuratsuki-Higashi, Kanazawa, Ishikawa, 920-8530, Japan.
Kosuke EndoDepartment of Pediatric Surgery, Medical Research Institute Kitano Hospital, 2-4-20, Ogi-Machi, Kita-Ku, Osaka, Osaka, 540-8480, Japan.
Hiroaki FukuzawaDepartment of Pediatric Surgery, Medical Research Institute Kitano Hospital, 2-4-20, Ogi-Machi, Kita-Ku, Osaka, Osaka, 540-8480, Japan.
Masahito SatoDepartment of Pediatric Surgery, Medical Research Institute Kitano Hospital, 2-4-20, Ogi-Machi, Kita-Ku, Osaka, Osaka, 540-8480, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe Nuss procedure is widely applied for the treatment of pectus excavatum (PE); however, postoperative infection remains a significant concern. Herein, we evaluated the postoperative outcomes and risk factors for postoperative infections following the Nuss procedure.

methodsThis study comprised a retrospective review of 112 cases of PE treated via the Nuss procedure between January 2019 and March 2024. Postoperative infection control measures, including thorough disinfection of the surgical field and perioperative intravenous administration of cefazolin, were ensured in all cases. Patient characteristics, surgical outcomes, and postoperative complications were analyzed, and risk factors for postoperative infection were assessed via multivariate analysis.

resultsPostoperative complications were observed in 17 cases (15.2%), including 6 (5.4%) with infection. Atopic dermatitis (AD) was significantly more common in the infection group (4/6, 66.7%) than in the non-infection group (8/106, 7.6%, p < 0.01). Multivariate analysis further identified the use of topical steroid medications for AD as the only independent risk factor for postoperative infection (Odds Ratio: 51.0, 95% CI: 7.12-366.0). Notably, two infections occurred beyond the typical 90-day surveillance period.

conclusionsAD is a significant risk factor for postoperative infection following the Nuss procedure, particularly when managed with topical steroid medications. These results suggest that patients with AD undergoing this procedure require meticulous preoperative management, rigorous infection control measures, and extended follow-up owing to the continued risk of infection throughout the bar placement period.

Indexed as

Funnel ChestOrthopedic ProceduresSurgical Wound InfectionAdolescentChildFemaleHumansMaleRetrospective StudiesRisk FactorsTreatment OutcomeYoung AdultAtopic dermatitisNuss procedurePectus excavatumPostoperative infectionRisk factors

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PMID40632389

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.