ArticleActa neurochirurgica. Supplement2025
New Classification of the Degree of Cerebrovascular Insufficiency in Patients with Moyamoya Disease Measured According to ASL-MRI Perfusion.
Article in Acta neurochirurgica. Supplement, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionWe aimed to classify different degrees of cerebrovascular insufficiency (CVI) in patients with moyamoya disease (MMD) by measuring cerebral blood flow (CBF) and distinguishing arterial transit artifacts (ATAs) on arterial spin labeling (ASL) magnetic resonance imaging (MRI).
methodsThe study included 121 images of patients with MMD who underwent ASL-MRI before and after surgical treatment (242 hemispheres). On ASL-CBF maps, regions of interest (ROIs) were manually drawn in each hemisphere in seven zones. Quantitative and qualitative patterns of arterial transit artifacts (ATA) were studied. Analysis of variance (ANOVA) was used for group comparisons.
resultsDistinguished patterns were divided into four statistically significant degrees on the basis of CBF values and the presence of ATA: degree 0 with normal CBF values and without ATAs (n = 59) (CBF 60.37-68.64 mL/100gxmin); degree 1 with moderate decreased CBF and with ATAs (n = 97) (CBF 55.82-62.16); degree 2 with significantly decreased CBF and with ATAs (n = 64) (CBF 25.64-28.96); and degree 3 with very low CBF and without ATAs (n = 22) (CBF 15.58-19.97). All groups exhibited significant differences between the value of CBF in all cortical territories (p < 0.01). Distinguished patterns had high correlations between Suzuki stage, the severity of ischemic disease, and neurologic deficit.
conclusionThe revealed ASL-MRI patterns correspond to the degree of CVI, the stage of the disease, and the clinical symptoms and can be used for assessment in the patients with moyamoya disease.
Indexed as
Identifiers
40632262What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.