Evidence map›Paper›PMID 40632224›Full record

Trial reportArchives of orthopaedic and trauma surgery2025

Clinically relevant differences in stress shielding between two short-stemmed femoral prostheses.

Felix Werneburg, Annabell Herntrich, Julia Dietz, David Wohlrab, Natalia Gutteck, Delank Karl-Stefan, Alexander Zeh

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in Archives of orthopaedic and trauma surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Felix WerneburgDepartment of Orthopedic and Trauma Surgery, University Hospital Halle (Saale), Martin Luther University Halle-Wittenberg, Ernst-Grube Str. 40, 06120, Halle, Germany. felix.werneburg@uk-halle.de.
Annabell HerntrichFaculty of Medicine, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.
Julia DietzDepartment of Orthopedics and Trauma Surgery, Dölau Hospital, Halle (Saale), Germany.
David WohlrabDepartment of Orthopedic and Trauma Surgery, University Hospital Halle (Saale), Martin Luther University Halle-Wittenberg, Ernst-Grube Str. 40, 06120, Halle, Germany.
Natalia GutteckDepartment of Orthopedic and Trauma Surgery, University Hospital Halle (Saale), Martin Luther University Halle-Wittenberg, Ernst-Grube Str. 40, 06120, Halle, Germany.
Delank Karl-StefanDepartment of Orthopedic and Trauma Surgery, University Hospital Halle (Saale), Martin Luther University Halle-Wittenberg, Ernst-Grube Str. 40, 06120, Halle, Germany.
Alexander ZehDepartment of Orthopedic and Trauma Surgery, University Hospital Halle (Saale), Martin Luther University Halle-Wittenberg, Ernst-Grube Str. 40, 06120, Halle, Germany. alexander.zeh@uk-halle.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundShort-stemmed endoprostheses were developed to implement proximal load transmission and thus avoid stress-shielding in the proximal femur. Various prosthesis systems have been developed, which are discussed in the literature regarding stress shielding, clinical outcome, and long-term implant stability.

methodsIn this prospective randomized study, 52 patients (27 male, 25 female; average age 60.8 years) with conservatively unsuccessfully treated coxarthrosis were implanted with either a Nanos™ or Optimys™ short-stem prosthesis. Assessment included Gruen-zone based DEXA examinations immediately postoperatively and at one year to evaluate bone mineral density (BMD) and stress shielding, along with clinical outcomes using the Harris Hip Score (HHS). Radiographic measurements included offset (OFF), caput-collum-diaphyseal angle (CCD), leg length (LL), stem migration and inclination, and the occurrence of radiolucent lines (RL), assessed preoperatively, postoperatively, and at 12 months.

resultsDEXA showed differing stress-shielding profiles between stem types, favoring Optimys™ for BMD preservation. The Nanos™ group exhibited significantly greater BMD reduction in Gruen zones 1 (- 10.1%; p = 0.001), 4 (- 3.2%; p = 0.02), and 7 (- 21.3%; p = 0.001), whereas Optimys™ showed a significant decrease only in zone 7 (- 16.2%; p = 0.001). Although OFF, CCD, and LL changed significantly within groups postoperatively (p < 0.05), no statistically significant differences were found between the two stem designs in the final postoperative measurements (all p > 0.05). Stem migration remained clinically irrelevant in both groups. A statistically significant intra-group change was observed only in the Optimys™ group (Nanos™: 1.7 mm, p = 0.13; Optimys™: 2.5 mm, p = 0.01). Similarly, a small but statistically significant change in stem inclination was observed within both groups (Nanos™: 2.2°, p = 0.002; Optimys™: 1.5°, p = 0.01). Clinical improvement as measured by the Harris Hip Score (HHS) was excellent in both groups, with no significant differences between systems (Nanos™ pre/post: 52.0 / 98.0; Optimys™ pre/post: 51.6 / 97.0; both p < 0.001).

conclusionsWhen compared, the Optimys stem demonstrated reduced stress shielding through improved proximal load transmission, resulting in significantly better preservation of bone mineral density in the proximal femur. LEVEL OF EVIDENCE: Ib.

Indexed as

Arthroplasty, Replacement, HipHip ProsthesisOsteoarthritis, HipProsthesis DesignAbsorptiometry, PhotonAgedBone DensityFemaleFemurHumansMaleMiddle AgedProspective StudiesStress, MechanicalBone mineral densityFemoral bone remodelingShort-stem hip prosthesisStress shielding

Identifiers

PMID40632224
PMCPMC12241186

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.