ArticleMicrobiology spectrum2025
Epstein-Barr virus (EBV) infection of endothelial cells via endocytosis is associated with a poor prognosis in nasopharyngeal carcinoma.
Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Core regulatory mechanisms of the PD-L1 axis and clinical strategies for immune escape and immunotherapy response in nasopharyngeal carcinoma.Translational oncology · 2026Review
- Virus-induced endothelial senescence as a cause and driving factor for ME/CFS and long COVID: mediated by a dysfunctional immune system.Cell death & disease · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Epstein-Barr virus (EBV) infection is strongly associated with several malignancies, including nasopharyngeal carcinoma (NPC), Burkitt lymphoma, and certain gastric cancers, though its potential to infect endothelial cells (ECs) and the consequent pathological implications remain poorly understood. This study demonstrates through analysis of 99 NPC clinical samples (primary tumors) that Epstein-Barr virus-encoded small RNAs (EBERs) positivity in ECs significantly correlates with N stage (lymphatic metastasis,
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Registered trials
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