Evidence map›Paper›PMID 40631679›Full record

ReviewSmall (Weinheim an der Bergstrasse, Germany)2025

Augmented 3D Printing for Multiscale Microphysiological Systems.

Kyeong Seob Hwang, Jiyoung Song, Hyun Wook Kang, Jongbaeg Kim, Cheol Woo Ha, Nakwon Choi, Seokyoung Bang, Hong Nam Kim

Abstract readReview
In one paragraph

Review in Small (Weinheim an der Bergstrasse, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Augmented 3D Printing for Multiscale Microphysiological Systems.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kyeong Seob HwangBrain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea.
Jiyoung SongBrain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea.
Hyun Wook KangSchool of Mechanical Engineering, Korea University, Seoul, 02841, Republic of Korea.
Jongbaeg KimSchool of Mechanical Engineering, Yonsei University, Seoul, 03722, Republic of Korea.
Cheol Woo HaKorea Additive Manufacturing Innovation Center, Korea Institute of Industrial Technology, Siheung-si, 15014, Republic of Korea.
Nakwon ChoiDepartment of Biomedical Sciences, College of Medicine, Korea University, Seoul, 02841, Republic of Korea.
Seokyoung BangDepartment of Biomedical Engineering, Dongguk University, Goyang, 10326, Republic of Korea.
Hong Nam KimBrain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea.ORCID 0000-0002-0329-0029

Funding

KIST Institutional Program 2E33712Korea Environment Industry & Technology InstituteKorea Ministry of Environment RS-2025-02223058Korean government RS-2024-00331678Korean government RS-2024-00332024Korean government RS-2024-00346657Korean government RS-2024-00350442Korean government RS-2024-00395393Korean government RS-2024-00411952Korean government RS-2024-00424551Ministry of Food and Drug Safety, Republic of KoreaNational Research Foundation of Korea
6 · The paper itself

Abstract

Microphysiological systems (MPS) can recapitulate physiological features of human organs; however, existing engineering techniques are limited to fabricating sophisticated and functional MPS. Although 3D printing offers the potential to enhance the complexity of MPS and simplify the fabrication process, existing 3D-printed MPS suffer from challenges in fabricating multiscale structures spanning nanometers to centimeters. Recent studies suggested that these issues can be addressed by integrating multiscale ancillary techniques into 3D printing. In this review, an overview of augmented 3D-printing techniques is provided, combined with multiscale ancillary techniques for multiscale MPS fabrication, which are termed augmented 3D-printing techniques. It starts by providing an overview of 3D-printing methods and relevant multiscale ancillary techniques. Then, recent developments are highlighted in augmented 3D-printed MPS that show features that surpass those of conventional systems. This augmented approach opens the door to MPS with more physiologically relevant structures and functions, thereby marking a significant step forward in next-generation tissue engineering.

Indexed as

Printing, Three-DimensionalHumansMicrophysiological SystemsTissue Engineering3D printingaugmented 3D printingmicrophysiological systemmultiscale ancillary techniques

Identifiers

PMID40631679
PMCPMC12571220

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.