Evidence map›Paper›PMID 40631641›Full record

ArticleJournal of paediatrics and child health2025

The Unintended Impact of COVID-19 Associated Non-Pharmaceutical Interventions on Paediatric Hospital Admissions: An Interrupted Time Series Analysis.

Mitchell T G Pratt, Huong Le, Ashleigh Lin, Ariel Mace, Christopher C Blyth, Hannah C Moore

Abstract read
In one paragraph

Article in Journal of paediatrics and child health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mitchell T G PrattSchool of Medicine, Faculty of Health and Medical Sciences, The University of Western Australia, Perth, Australia.ORCID 0000-0003-3584-4193
Huong LeWesfarmers Centre for Vaccines and Infectious Diseases, The Kids Research Institute Australia, University of Western Australia, Perth, Australia.
Ashleigh LinSchool of Population and Global Health, University of Western Australia, Perth, Australia.
Ariel MaceWesfarmers Centre for Vaccines and Infectious Diseases, The Kids Research Institute Australia, University of Western Australia, Perth, Australia.
Christopher C BlythWesfarmers Centre for Vaccines and Infectious Diseases, The Kids Research Institute Australia, University of Western Australia, Perth, Australia.
Hannah C MooreWesfarmers Centre for Vaccines and Infectious Diseases, The Kids Research Institute Australia, University of Western Australia, Perth, Australia.

Funding

National Health and Medical Research Council Emerging Leadership Fellowships 2010063Perron Foundation FellowshipsWA Near-Miss Awards Future Health Reserach and Inovation FundWesfarmers Centre for Vaccines and Infectious Disease Clinician-Scientist Partnership
6 · The paper itself

Abstract

aimCOVID-19 related non-pharmaceutical interventions (NPIs) disrupted global healthcare utilisation, with notable declines in infection related paediatric hospitalisations. We aimed to identify non-infectious paediatric conditions for which the incidence of hospital admissions increased during the introduction and alleviation of NPIs in 2020.

methodsWe examined anonymous hospitalisation data from Perth's sole tertiary paediatric hospital (Jan 2015-Dec 2020), according to pre-defined age groups (0-4 years, 5-9 years, 10-16 years and 0-16). We identified the most frequent non-infectious diagnoses in these age groups over five different NPI periods. We quantified the impact of NPIs on admissions for the most frequent diagnosis groups (perinatal disorders, mental disorders) using interrupted time series (ITS) analysis.

resultsFollowing implementation of NPIs, admission rates for perinatal disorders amongst 0-4 year-olds increased by 18% (IRR = 1.18 [95% CI: 1.04-1.35]). ITS analysis revealed non-significant changes in admissions for mental disorders in 10-16 year-olds (IRR = 0.91 [95% CI: 0.79-1.06]). The incidence of eating disorders, however, increased significantly following the introduction of NPIs (IRR = 1.60 [95% CI: 1.14-2.25]).

conclusionsChanges in admissions for perinatal disorders and eating disorders highlight the unintended impact of COVID-19 associated NPIs on paediatric health. Amongst mental disorders more generally, it is possible that admission rates in 2020 may have been greater had COVID-19 associated NPIs not disrupted pre-pandemic trends. These findings aid our understanding of social factors mediating paediatric disease and may improve healthcare delivery in a post-pandemic era.

Indexed as

COVID-19HospitalizationHospitals, PediatricPatient AdmissionAdolescentAustraliaChildChild, PreschoolFemaleHumansInfantInfant, NewbornInterrupted Time Series AnalysisMaleMental DisordersSARS-CoV-2childCOVID‐19feeding and eating disordershospitalisationinfantinterrupted times series analysisnewbornnon‐pharmaceutical interventionpandemicsperinatal

Identifiers

PMID40631641
PMCPMC12455533

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.