Evidence map›Paper›PMID 40631435›Full record

ArticleNeurourology and urodynamics2025

Utilizing Predictive Analytics to Understand Neurogenic Bladder Symptom Score (NBSS) Variations in Adults With Acquired Spinal Cord Injury.

Mehran Nejad-Mansouri, Daniel Lizotte, Jeremy Myers, Sean Elliott, John T Stoffel, Sara Lenherr, Rhiannon Lyons, Tianyue Zhong, Blayne Welk

Abstract read
In one paragraph

Article in Neurourology and urodynamics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mehran Nejad-MansouriDepartment of Surgery, Western University, London, Ontario, Canada.
Daniel LizotteDepartment of Epidemiology and Biostatistics, Western University, London, Ontario, Canada.
Jeremy MyersDepartment of Surgery, Division of Urology, University of Utah, Salt Lake City, Utah, USA.ORCID https://orcid.org/0000-0002-5786-1552
Sean ElliottDepartment of Urology, University of Minnesota, Minneapolis, Minnesota, USA.ORCID https://orcid.org/0000-0002-5280-2449
John T StoffelDepartment of Urology, University of Michigan, Ann Arbor, Michigan, USA.ORCID https://orcid.org/0000-0002-5503-4940
Sara LenherrDepartment of Surgery, Division of Urology, University of Utah, Salt Lake City, Utah, USA.
Rhiannon LyonsDepartment of Epidemiology and Biostatistics, Western University, London, Ontario, Canada.
Tianyue ZhongDepartment of Epidemiology and Biostatistics, Western University, London, Ontario, Canada.
Blayne WelkDepartment of Surgery, Western University, London, Ontario, Canada.ORCID https://orcid.org/0000-0001-7093-558X

Funding

This study was partially supported through a Patient-centered outcomes research institute (PCORI) award (CER14092138).
6 · The paper itself

Abstract

introductionIndividuals with spinal cord injury (SCI) have varying bladder health trajectories after their injury. We explored whether a predictive machine learning model could identify which variables impact urinary symptoms.

methodsWe used 238 variables from the Neurogenic Bladder Research Group SCI registry for a Decision Tree analysis (eCHAID technique). The primary outcomes were the baseline Neurogenic Bladder Symptom Score (NBSS), and the change from the baseline NBSS at 1-year follow up (measured as better/worse than the median change).

resultsAmong the 1479 participants, mean baseline NBSS was 24.16 ± 0.28 (standard error of the mean). Our decision tree that evaluated the NBSS at baseline predicted that individuals with a suprapubic tube/urostomy as their primary bladder management method and good bowel QOL at baseline had the lowest (best) mean baseline NBSS at 13.44 ± 0.83. In contrast, females with baseline spontaneous voiding had the highest (worst) mean baseline NBSS at 34.42 ± 1.05. Our second decision tree evaluated the change in the NBSS at 1-year follow-up. Of the 711 participants that performed better than the median change (i.e., improved), 45% were accounted for jointly by women who did not use bladder relaxing medications at baseline, and men without a history of prior urinary tract infections who used a single bladder management method at follow-up. The predictive capacity the decision tree was 57%.

conclusionsDecision tree models help identify combinations of patient characteristics which correlate with urinary symptoms after SCI. However, there was a limited predictive capacity of the decision tree to forecast future bladder symptoms.

Indexed as

Machine LearningSpinal Cord InjuriesUrinary Bladder, NeurogenicAdultDecision TreesFemaleHumansMaleMiddle AgedPredictive Value of TestsRegistriesUrinary Bladderdecision tree analysisneurogenic bladderquality of lifespinal cord injury

Identifiers

PMID40631435
PMCPMC12319491

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.